黑色素瘤小鼠模型的临床病理特征
Clinicopathological characterization of mouse models of melanoma.
作者信息
Ferguson Blake, Soyer H Peter, Walker Graeme J
机构信息
Queensland Institute of Medical Research, 300 Herston Road, Herston, Queensland, 4006, Australia.
出版信息
Methods Mol Biol. 2015;1267:251-61. doi: 10.1007/978-1-4939-2297-0_11.
Mouse models of melanoma have proven invaluable in the delineation of key molecular events involved in disease progression in humans and provide potential preclinical models for therapeutic testing (Damsky and Bosenberg, Pigment Cell Melanoma Res 25(4):404-405, 2012; Walker et al., Pigment Cell Melanoma Res 24(6):1158-1176, 2011). Here we concentrate on the clinicopathological analysis of melanocytic tumors.
黑色素瘤的小鼠模型已被证明在描绘人类疾病进展中涉及的关键分子事件方面具有不可估量的价值，并为治疗测试提供了潜在的临床前模型（Damsky和Bosenberg，《色素细胞与黑色素瘤研究》25(4):404 - 405，2012；Walker等人，《色素细胞与黑色素瘤研究》24(6):1158 - 1176，2011）。在此，我们专注于黑素细胞肿瘤的临床病理分析。
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