Saxby Alexander J, Gowdy Claire, Fandiño Marcela, Chadha Neil K, Kozak Frederick K, Sargent Michael A, Lea Jane
Division of Pediatric Otolaryngology, Head and Neck Surgery, BC Children's Hospital, 4480 Oak Street, Vancouver, BC V6H 3N1, Canada.
Department of Radiology, BC Children's Hospital, 4480 Oak Street, Vancouver, BC V6H 3N1, Canada.
Int J Pediatr Otorhinolaryngol. 2015 Mar;79(3):411-8. doi: 10.1016/j.ijporl.2015.01.001. Epub 2015 Jan 14.
Establishing the prevalence of semicircular canal dehiscence in a pediatric population using temporal bone CT imaging.
Retrospective analysis of all temporal bone CT scans during a 5-year period (2007-2012).
CT scan images were reformatted in the plane of the canals and assessed by two independent reviewers with a third to resolve disagreement. Detailed chart review was performed for those found to have dehiscence. Superior and posterior canals were classified as "dehiscent", "possibly dehiscent", "thin" or "normal" for each case.
649 temporal bones were assessed from 334 children (under 18 years of age). The prevalence rate of superior canal dehiscence (SCD) was 1.7% (3.3% of individuals). Posterior canal dehiscence (PCD) was present in 1.2% (2.1% of individuals). There were no cases of bilateral SCD, and one case of bilateral PCD. Age under 3 years was associated with a higher prevalence of thinning but not dehiscence. Congenital inner ear malformation was not related to a higher probability of dehiscence. The superior petrosal sinus was associated with the SCD in three cases (27.3%). Retrospective chart review highlighted possible vestibular symptoms in 3/11 patients with SCD (27.3%).
This forms the largest pediatric study of canal dehiscence to date. This study's prevalence rate is significantly lower than previous reports. The identified association with overlying venous structures may reflect the etiological process involved. The occurrence in children supports the hypothesis of a congenital predisposition for development of canal dehiscence syndrome.
利用颞骨CT成像确定儿科人群中半规管裂开的患病率。
对5年期间（2007 - 2012年）所有颞骨CT扫描进行回顾性分析。
CT扫描图像在半规管平面进行重组，并由两名独立审阅者评估，如有分歧则由第三名审阅者解决。对发现有裂开的病例进行详细的病历审查。对每个病例的上半规管和后半规管分类为“裂开”、“可能裂开”、“薄”或“正常”。
对334名18岁以下儿童的649块颞骨进行了评估。上半规管裂开（SCD）的患病率为1.7%（个体的3.3%）。后半规管裂开（PCD）的患病率为1.2%（个体的2.1%）。没有双侧SCD病例，有1例双侧PCD病例。3岁以下儿童出现变薄的患病率较高，但裂开患病率不高。先天性内耳畸形与裂开的较高概率无关。上岩窦在3例SCD病例中与之相关（27.3%）。回顾性病历审查显示，11例SCD患者中有3例（27.3%）可能有前庭症状。
这是迄今为止最大规模的关于半规管裂开的儿科研究。本研究的患病率明显低于先前报告。所确定的与上方静脉结构的关联可能反映了所涉及的病因过程。在儿童中的发生支持了半规管裂开综合征先天性易患性的假说。
