Brignardello-Petersen Romina, Carrasco-Labra Alonso, Glick Michael, Guyatt Gordon H, Azarpazhooh Amir
J Am Dent Assoc. 2015 Feb;146(2):94-101.e1. doi: 10.1016/j.adaj.2014.12.002.
Questions regarding harm are common in dental practice. Observational, nonrandomized studies (that is, cohort studies and case-control studies) are the designs used by investigators to answer most of these questions. A critical appraisal of these studies should include an assessment of the risk of bias, the results, and the applicability of the study. The authors provide the concepts and guidelines that dentists can apply to most effectively use articles regarding harm to guide their clinical practice.
Dentists who wish to inform their clinical decisions regarding questions of harm can use these guidelines to decide what type of studies to search, define the specific question of interest to search efficiently for these studies, and critically appraise an article about harm.
在牙科实践中,关于危害的问题很常见。观察性、非随机研究(即队列研究和病例对照研究)是研究人员用来回答大多数此类问题的设计方法。对这些研究的严格评估应包括对偏倚风险、研究结果和研究适用性的评估。作者提供了一些概念和指南,牙医可运用这些概念和指南最有效地利用有关危害的文章来指导临床实践。
希望为有关危害问题的临床决策提供依据的牙医,可以使用这些指南来决定搜索何种类型的研究,明确感兴趣的具体问题以便有效地搜索这些研究,并对一篇关于危害的文章进行严格评估。