Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, 1153 Centre Street, Suite 4970, Boston, MA, 02130, USA,
Curr Neurol Neurosci Rep. 2015 Mar;15(3):4. doi: 10.1007/s11910-015-0528-2.
Chronic daily headaches (CDH) is a descriptive term used for patients who experience headaches on at least 15 days or more out of the month; for at least 3 months, irrespective of the underlying headache etiology. It is a syndrome that affects many people, usually with an underlying primary headache disorder, leading to a reduction in quality of life. The two most common underlying primary headaches are migraines and tension-type headaches. The prevalence is about 4%, and research is emerging on risk factors and comorbidities. The first step when approaching a patient with chronic daily headaches is to rule out secondary causes. Once that is done, the goal is to effectively reduce the days of headache through preventive treatment as well as complementary therapies. This also often involves limiting the use of abortive therapy to avoid medication-overuse headaches (MOH). The pathophysiology, although not fully understood, is thought to be related to central sensitization along with "neurogenic inflammation." Chronic daily headaches can be difficult to treat and at times require a tertiary specialized center.
慢性每日头痛(CDH)是用于描述那些每月头痛发作至少 15 天或更多天,持续至少 3 个月,无论潜在的头痛病因如何的患者。这是一种影响许多人的综合征,通常与潜在的原发性头痛障碍有关,导致生活质量下降。两种最常见的潜在原发性头痛是偏头痛和紧张型头痛。患病率约为 4%,关于风险因素和合并症的研究正在出现。当治疗慢性每日头痛患者时,第一步是排除继发性病因。一旦完成,目标是通过预防治疗和补充疗法有效减少头痛天数。这通常还涉及限制使用中止治疗以避免药物过度使用性头痛(MOH)。尽管其病理生理学尚未完全了解,但据认为与中枢敏化以及“神经源性炎症”有关。慢性每日头痛可能难以治疗,有时需要三级专业中心。