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[组织工程在手部屈指肌腱损伤重建中的应用]

[Use of tissue engineering in the reconstruction of flexor tendon injuries of the hand].

作者信息

Bíró Vilmos

机构信息

Pécs Hajnóczy u. 25/A, II. em. 2. 7633.

出版信息

Orv Hetil. 2015 Feb 8;156(6):216-20. doi: 10.1556/OH.2015.30094.

Abstract

In his literary analysis, the author describes a novel method applied in the reconstruction of flexor tendon injuries of the hand. This procedure is named tissue engineering, and it is examined mainly under experimental circumstances. After definition of the method and descriptions of literary preliminaries the author discusses the healing process of the normal tendon tissue, then development of the scaffold, an important step of tissue engineering is described. After these topics the introduction of the pluripotent mesenchymal stem cells into the scaffold, and proliferation of these cells and development of the sliding systems are presented. The mechanical resisting ability of the formed tendon tissue is also discussed. Finally, the author concludes that as long as results of experimental research cannot be successfully applied into clinical practice, well-tried tendon reconstruction operations and high quality postoperative rehabilitation are needed.

摘要

在其文学分析中,作者描述了一种应用于手部屈肌腱损伤重建的新方法。该程序被称为组织工程,主要在实验环境下进行研究。在定义该方法并描述文献综述后,作者讨论了正常肌腱组织的愈合过程,接着描述了支架的开发,这是组织工程的一个重要步骤。在这些主题之后,介绍了将多能间充质干细胞引入支架,以及这些细胞的增殖和滑动系统的发育。还讨论了形成的肌腱组织的机械抵抗能力。最后,作者得出结论,只要实验研究结果不能成功应用于临床实践,就需要尝试成熟的肌腱重建手术和高质量的术后康复。

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