一例位于鼻底的异位脑膜瘤。
An ectopic meningioma in nasal floor.
作者信息
Yang Xi-Hu, Liu Liu, Zhang Ping, Hu Yong-Jie
机构信息
From the *Department of Oral and Maxillofacial Surgery, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu; and †Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; and ‡Shanghai Key Laboratory of Stomatology, Shanghai, China.
出版信息
J Craniofac Surg. 2015 Mar;26(2):e88-90. doi: 10.1097/SCS.0000000000000546.
OBJECTIVE
Primary ectopic meningioma is a rare tumor and is usually limited to the paravertebral soft tissues. The aim of this study was to assist in the diagnosis and treatment of the tumor.
METHODS
A 16-year-old boy presented with a nasal floor mass. The computed tomographic scan suggested a neoplastic mass lesion in the nasal floor region, and primary diagnosis is sebaceous cyst. The patient received a surgical resection, and the histologic examinations showed that the lesion was characterized with spindle cells. Immunohistochemical staining showed that the tumor cells presented intense reactivity for epithelial membrane antigen and vimentin. Histologic examination and immunohistochemical staining confirmed the diagnosis of extracranial ectopic meningioma.
RESULTS
The patient received a radical surgical and immediate restoration of adjacent flap, and the patient fully recovered 1 week later.
CONCLUSIONS
The case highlights the fact that despite its rarity, ectopic meningioma should be considered as a differential diagnosis of any mass lesion in the head and neck region, especially when spindle cells are histologically observed.
目的
原发性异位脑膜瘤是一种罕见肿瘤，通常局限于椎旁软组织。本研究的目的是辅助该肿瘤的诊断与治疗。
方法
一名16岁男孩出现鼻底肿物。计算机断层扫描提示鼻底区域有肿瘤性肿块病变，初步诊断为皮脂腺囊肿。患者接受了手术切除，组织学检查显示病变以梭形细胞为特征。免疫组织化学染色显示肿瘤细胞对上皮膜抗原和波形蛋白呈强反应性。组织学检查和免疫组织化学染色确诊为颅外异位脑膜瘤。
结果
患者接受了根治性手术并立即进行相邻皮瓣修复，1周后完全康复。
结论
该病例突出了这样一个事实，即尽管异位脑膜瘤罕见，但对于头颈部任何肿块病变，尤其是在组织学上观察到梭形细胞时，都应将其视为鉴别诊断之一。
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