Arno Sally, Bell Christopher P, Uquillas Carlos, Borukhov Ilya, Walker Peter S
Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, New York, New York.
J Orthop Res. 2015 Apr;33(4):584-90. doi: 10.1002/jor.22809. Epub 2015 Jan 28.
The purpose of this study was to determine if a horizontal cleavage lesion (HCL) of the posterior horn of the medial meniscus would result in changes to tibiofemoral contact mechanics, as measured by peak contact pressure and contact area, which can lead to cartilage degeneration. To study this, 10 cadaveric knees were tested in a rig where forces were applied (500 N Compression, 100 N shear, 2.5 Nm Torque) and the knee dynamically flexed from -5° to 135°, as peak contact pressure and contact area were recorded. After testing of the intact knee, a horizontal cleavage lesion was created arthroscopically and testing repeated. The Wilcoxon signed-rank test was used to determine if there were differences in peak contact pressure and contact area between the intact knee and that with the HCL. A statistically significant increase in peak contact pressure of 13%, on average, and a decrease in contact area of 6%, on average, was noted following the HCL. This suggests that a horizontal cleavage lesion will result in small but statistically significant changes in tibiofemoral contact mechanics which may lead to cartilage degeneration.
本研究的目的是确定内侧半月板后角的水平劈裂损伤（HCL）是否会导致胫股关节接触力学发生变化，通过峰值接触压力和接触面积来衡量，而这可能会导致软骨退变。为了研究这一点，在一个试验装置中对10个尸体膝关节进行测试，施加力（500 N压缩力、100 N剪切力、2.5 Nm扭矩），膝关节从-5°动态屈曲到135°，同时记录峰值接触压力和接触面积。在对完整膝关节进行测试后，通过关节镜制造水平劈裂损伤并重复测试。采用Wilcoxon符号秩检验来确定完整膝关节与有HCL的膝关节之间在峰值接触压力和接触面积上是否存在差异。结果发现，HCL后平均峰值接触压力有13%的显著增加，平均接触面积有6%的减小。这表明水平劈裂损伤将导致胫股关节接触力学发生虽小但具有统计学意义的变化，这可能会导致软骨退变。
