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慢性血液透析患者气肿性肾盂肾炎的成功医学治疗

Successful medical treatment of emphysematous pyelonephritis in chronic hemodialysis.

作者信息

Vlachopanos Georgios, Kassimatis Theodoros, Zerva Adamantia, Kokkona Anastasia, Stavroulaki Eirini, Zacharogiannis Charilaos, Agrafiotis Athanasios

机构信息

Department of Nephrology, "Asklepieion" General Hospital, Athens, Greece.

出版信息

Hemodial Int. 2015 Oct;19(4):E54-8. doi: 10.1111/hdi.12274. Epub 2015 Feb 3.

Abstract

Emphysematous pyelonephritis (EPN) is a life-threatening renal infection caused by gas-producing bacteria and fungi. It usually occurs in patients with diabetes and patients with urinary tract obstruction. A combination of systemic antibiotics, percutaneous catheter drainage, or open nephrectomy is typically required to achieve cure. Because of grim prognosis, resorting to interventional methods is frequently inevitable. We report the case of a 77-year-old woman with diabetes and end-stage renal disease on chronic hemodialysis that presented with fever and left flank pain. A bubbly gas pattern inside the left kidney was demonstrated on abdominal computed tomography scan and blood cultures grew Escherichia coli. She was successfully treated solely with systemic antibiotics. This highlights the fact that prompt recognition of imaging findings associated with benign prognosis is essential for a favorable outcome. It allows for an effective management avoiding high-risk interventions, especially in frail patients with multiple comorbidities. Finally, we review all published cases of EPN in chronic dialysis patients.

摘要

气肿性肾盂肾炎(EPN)是一种由产气细菌和真菌引起的危及生命的肾脏感染。它通常发生在糖尿病患者和尿路梗阻患者中。通常需要联合使用全身抗生素、经皮导管引流或开放性肾切除术才能治愈。由于预后严峻,采用介入方法往往不可避免。我们报告了一例77岁患有糖尿病和终末期肾病且正在接受慢性血液透析的女性患者,她出现发热和左侧胁腹疼痛。腹部计算机断层扫描显示左肾内有气泡样气体影像,血培养结果为大肠杆菌生长。她仅通过全身抗生素治疗就成功治愈。这突出了一个事实,即迅速识别与良性预后相关的影像学表现对于取得良好结果至关重要。这有助于进行有效的管理,避免高风险干预,尤其是在患有多种合并症的体弱患者中。最后,我们回顾了所有已发表的慢性透析患者气肿性肾盂肾炎病例。

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