Gélisse Philippe, Crespel Arielle
Epilepsy Unit, Hôpital Gui de Chauliac, Montpellier Research Unit URCMA (Unité de recherche sur les comportements et mouvements anormaux), INSERM, U661, Montpellier, France.
Epileptic Disord. 2015 Mar;17(1):95-6. doi: 10.1684/epd.2014.0719.
Myoclonic status epilepticus or mixed absence-myoclonic status is uncommon in juvenile myoclonic epilepsy (JME), often precipitated by sleep deprivation, withdrawal of medication, or inadequate antiepileptic drugs (Thomas et al., 2006; Crespel et al., 2013). Such episodes respond well to benzodiazepines or valproate (Crespel et al., 2013). We present the video-EEG of a 24-year-old woman with JME and bipolar disorder. She had a confusional state five days after withdrawal of clonazepam (14 mg/d) and introduction of oxazepam (200 mg/d), followed by catatonic stupor with subtle myoclonus of the face and the arms. The EEG showed absence status (figures 1, 2), which stopped after IV injection of clonazepam (1 mg) (figure 3). Consciousness returned to normal [Published with video sequence and figures (1)].
肌阵挛性癫痫持续状态或失神-肌阵挛混合性癫痫持续状态在青少年肌阵挛性癫痫（JME）中并不常见，常由睡眠剥夺、停药或抗癫痫药物不足引发（托马斯等人，2006年；克雷斯佩尔等人，2013年）。此类发作对苯二氮䓬类药物或丙戊酸盐反应良好（克雷斯佩尔等人，2013年）。我们展示了一名患有JME和双相情感障碍的24岁女性的视频脑电图。在停用氯硝西泮（14毫克/天）并引入奥沙西泮（200毫克/天）五天后，她出现了意识模糊状态，随后出现紧张性木僵，并伴有面部和手臂轻微肌阵挛。脑电图显示失神状态（图1、2），静脉注射氯硝西泮（1毫克）后停止（图3）。意识恢复正常[随视频序列和图（1）发表]
