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主动脉旁T4期胸段食管鳞状细胞癌根治性放化疗后双侧开胸挽救性食管切除术:1例报告

Salvage esophagectomy under bilateral thoracotomy after definitive chemoradiotherapy for aorta T4 thoracic esophageal squamous cell carcinoma: Report of a case.

作者信息

Nagaki Yushi, Sato Yusuke, Motoyama Satoru, Yoshino Kei, Sasaki Tomohiko, Wakita Akiyuki, Imai Kazuhiro, Saito Hajime, Minamiya Yoshihiro

机构信息

Department of Thoracic Surgery, Akita University Graduate School of Medicine, Akita 010-8543, Japan.

Department of Thoracic Surgery, Akita University Graduate School of Medicine, Akita 010-8543, Japan.

出版信息

Int J Surg Case Rep. 2015;8C:76-80. doi: 10.1016/j.ijscr.2015.01.018. Epub 2015 Jan 14.

DOI:10.1016/j.ijscr.2015.01.018
PMID:25644553
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4353940/
Abstract

INTRODUCTION

The surgical technique for esophagectomy to treat esophageal malignancies has been improved over the past several decades. Nevertheless, it remains extremely difficult to surgically treat patients with locally advanced T4b tumors invading the aorta or respiratory tract.

PRESENTAION OF CASE

A 37-year-old Japanese man was diagnosed with T4b (descending aorta) N2M0, Stage IIIC middle thoracic esophageal squamous cell carcinoma. He was initially treated with definitive CRT followed by 3 courses of DCF. After the DCF, CT showed that the main tumor had shrunk and appeared to have separated from the descending aorta. Therefore we decided to perform a salvage esophagectomy. Because we needed the ability to closely observe the site of invasion to determine whether aortic invasion was still present, half the esophageal resection was performed under right thoracotomy, but the final resection at the invasion site was performed under left thoracotomy. Consequently, the thoracic esophagus was safely removed and aortic replacement was avoided. The patient has now survived more than 30 months after the salvage esophagectomy with no additional treatment for esophageal cancer and no evidence of recurrent disease.

DISCUSSION

Because this and the previously reported procedures, each have particular advantages and disadvantages, one must contemplate and select an approach based on the situation for each individual patient.

CONCLUSION

Salvage esophagectomy through a right thoracotomy followed by careful observation of the invasion site for possible aortic replacement through a left thoracotomy is an optional procedure for these patients.

摘要

引言

在过去几十年中,用于治疗食管恶性肿瘤的食管切除术手术技术已有改进。然而,对于局部晚期T4b肿瘤侵犯主动脉或呼吸道的患者,手术治疗仍然极其困难。

病例介绍

一名37岁的日本男性被诊断为T4b(降主动脉)N2M0,IIIC期胸段食管鳞状细胞癌。他最初接受了根治性同步放化疗,随后进行了3个疗程的DCF化疗。DCF化疗后,CT显示主肿瘤缩小,似乎已与降主动脉分离。因此,我们决定进行挽救性食管切除术。由于我们需要能够密切观察侵犯部位,以确定是否仍存在主动脉侵犯,所以在右胸切开术下进行了一半的食管切除术,但在左胸切开术下进行了侵犯部位的最终切除术。结果,胸段食管被安全切除,避免了主动脉置换。该患者在挽救性食管切除术后已存活超过30个月,未接受额外的食管癌治疗,也没有复发疾病的迹象。

讨论

因为本病例及之前报道的手术方法各有优缺点,所以必须根据每个患者的具体情况考虑并选择一种方法。

结论

对于这些患者,通过右胸切开术进行挽救性食管切除术,然后通过左胸切开术仔细观察侵犯部位以考虑是否可能进行主动脉置换,是一种可供选择的手术方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d68/4353940/2eb75e675db1/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d68/4353940/ca4aec0f1de0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d68/4353940/2b0756817f50/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d68/4353940/ddf26c2fa9f0/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d68/4353940/f12aa18d5e26/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d68/4353940/2eb75e675db1/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d68/4353940/ca4aec0f1de0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d68/4353940/2b0756817f50/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d68/4353940/ddf26c2fa9f0/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d68/4353940/f12aa18d5e26/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d68/4353940/2eb75e675db1/gr5.jpg

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