Eriksson Carl O, Uyeki Timothy M, Christian Michael D, King Mary A, Braner Dana A V, Kanter Robert K, Kissoon Niranjan
1Division of Pediatric Critical Care, Department of Pediatrics, Oregon Health & Science University, Portland, OR. 2Influenza Division, National Center for Immunization and Respiratory Diseases, U.S. Centers for Disease Control and Prevention, Atlanta, GA. 3Department of Critical Care, Mount Sinai Hospital, Toronto, ON, Canada. 4Pediatric Critical Care Medicine, Seattle Children's Hospital and Harborview Medical Center, Seattle, WA. 5Pediatric Critical Care Medicine, Virginia Tech Carilion School of Medicine, Roanoke, VA. 6National Center for Disaster Preparedness, Columbia University, New York, NY. 7Departments of Pediatrics and Emergency Medicine, British Columbia's Children's Hospital, Vancouver, BC, Canada.
Pediatr Crit Care Med. 2015 Feb;16(2):97-103. doi: 10.1097/PCC.0000000000000358.
To provide clinicians with practical considerations for care of children with Ebola virus disease in resource-rich settings.
Review of the published medical literature, World Health Organization and government documents, and expert opinion.
There are limited data regarding Ebola virus disease in children; however, reported case-fatality proportions in children are high. Ebola virus may affect immune regulation and endothelial function differently in children than adults. Considerations for care of children with Ebola virus disease are presented.
Ebola virus disease is a severe multisystem disease with high mortality in children and adults. Hospitals and clinicians must prepare to provide care for patients with Ebola virus disease before such patients present for care, with particular attention to rigorous infection control to limit secondary cases. Although there is no proven specific treatment for Ebola virus disease, meticulous supportive care offers patients the best chance of survival.
为资源丰富环境下埃博拉病毒病患儿的护理提供临床实用考量。
对已发表医学文献、世界卫生组织及政府文件的综述,以及专家意见。
关于儿童埃博拉病毒病的数据有限;然而,报告的儿童病死率较高。埃博拉病毒对儿童免疫调节和内皮功能的影响可能与成人不同。本文提出了埃博拉病毒病患儿护理的相关考量。
埃博拉病毒病是一种严重的多系统疾病,在儿童和成人中死亡率都很高。医院和临床医生必须在埃博拉病毒病患者前来就诊之前做好为其提供护理的准备,尤其要注意严格的感染控制以限制二代病例。虽然尚无经证实的埃博拉病毒病特效治疗方法,但精心的支持性护理为患者提供了最佳的生存机会。