Harsten Andreas, Bandholm Thomas, Kehlet Henrik, Toksvig-Larsen Sören
Dept of Anesthesiology, Hässleholm Hospital and Lund University, Box 351, 281 25 Hässleholm, Sweden.
Physical Medicine & Rehabilitation Research-Copenhagen (PMR-C), Dept of Physical Therapy, Denmark; Dept of Orthopedic Surgery, Hvidovre Hospital, University of Copenhagen, Denmark; Clinical Research Centre, Hvidovre Hospital, University of Copenhagen, Denmark.
Knee. 2015 Mar;22(2):126-30. doi: 10.1016/j.knee.2014.12.010. Epub 2014 Dec 31.
Thigh tourniquet is commonly used in total knee arthroplasty (TKA) but may contribute to pain and muscle damage. Consequently, the reduction in knee-extension strength after TKA may be caused by quadriceps muscle ischaemia underneath the cuff.
To examine if not using a thigh tourniquet during surgery was more effective than using a thigh tourniquet in preserving knee-extension strength 48 h after fast-track TKA.
A total of 64 patients undergoing TKA were randomized (1:1) to the use of tourniquet (T-group) or no tourniquet (NT-group). In the T-group the tourniquet cuff pressure was based on the patient's systolic pressure and a margin of 100 mm Hg. It was inflated immediately before surgery and deflated as soon as surgery ended. The primary outcome was the change in knee-extension strength from pre-surgery to 48 h after surgery (primary end point). Secondary outcomes were pain, nausea, length of hospital stay (LOS) and periarticular swelling.
Knee-extension strength 48 h after surgery was substantially reduced by about 90% in both groups, with no statistically significant difference between groups (mean difference 1.5 N/kg, 95% CI 1.3-1.6). Among the secondary outcomes, the T-group had less bleeding during surgery (56 vs. 182 mL, P<0.01) compared with the NT-group. There was no difference in postoperative haemoglobin levels, pain, nausea, LOS or periarticular swelling between the groups.
Not using a thigh tourniquet during surgery was not superior in preserving knee-extension strength at the primary endpoint 48 h after fast-track TKA, compared to using a tourniquet.
大腿止血带常用于全膝关节置换术(TKA),但可能导致疼痛和肌肉损伤。因此,TKA术后膝关节伸展力量的下降可能是由于止血带下股四头肌缺血所致。
探讨在快速康复TKA术后48小时,术中不使用大腿止血带在保留膝关节伸展力量方面是否比使用大腿止血带更有效。
共有64例行TKA的患者被随机(1:1)分为使用止血带组(T组)和不使用止血带组(NT组)。在T组中,止血带袖带压力基于患者的收缩压并增加100 mmHg。在手术即将开始前充气,手术结束后立即放气。主要结局是从术前到术后48小时膝关节伸展力量的变化(主要终点)。次要结局包括疼痛、恶心、住院时间(LOS)和关节周围肿胀。
两组术后48小时膝关节伸展力量均大幅下降约90%,组间无统计学显著差异(平均差异1.5 N/kg,95% CI 1.3 - 1.6)。在次要结局中,与NT组相比,T组术中出血较少(56 vs. 182 mL,P<0.01)。两组术后血红蛋白水平、疼痛、恶心、LOS或关节周围肿胀无差异。
与使用止血带相比,在快速康复TKA术后48小时的主要终点上,术中不使用大腿止血带在保留膝关节伸展力量方面并不更优。