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骨科手术中的“患者血液管理”

"Patient blood management" in orthopaedic surgery.

作者信息

Canillas Fernando, Gómez-Ramírez Susana, García-Erce José Antonio, Pavía-Molina José, Gómez-Luque Aurelio, Muñoz Manuel

机构信息

Servicio de Cirugía Ortopédica y Traumatología, Hospital Cruz Roja, Madrid, España.

GIEMSA, Medicina Transfusional Perioperatoria, Facultad de Medicina, Universidad de Málaga, Málaga, España.

出版信息

Rev Esp Cir Ortop Traumatol. 2015 May-Jun;59(3):137-49. doi: 10.1016/j.recot.2014.11.005. Epub 2015 Jan 28.

Abstract

Orthopaedic and trauma surgical procedures (OTS) can lead to significant blood losses and acute postoperative anaemia, which in many cases requires allogeneic blood transfusions (ABT). The clinical, economic and logistical disadvantages of ABT have promoted the development of multidisciplinary and multimodal programs generically known as Patient Blood Management (PBM) programs, which have as their objective to reduce or eliminate the need for ABT and improve clinical outcomes. These programs are supported by the implementation of four groups of perioperative measures: (1) use of restrictive transfusion criteria; (2) stimulation of erythropoiesis; (3) reduction of bleeding; and (4) autologous blood transfusion. In this article, a review is presented of the effectiveness, safety and recommendations of applicable strategies in OTS, as well as the barriers and requirements to the development and implementation of PBM programs in this surgical specialty.

摘要

骨科与创伤外科手术(OTS)可导致大量失血及术后急性贫血,在许多情况下需要异体输血(ABT)。ABT在临床、经济和后勤方面的劣势推动了多学科和多模式方案的发展,这些方案通常被称为患者血液管理(PBM)方案,其目标是减少或消除ABT的需求并改善临床结局。这些方案通过实施四组围手术期措施来支持:(1)使用限制性输血标准;(2)刺激红细胞生成;(3)减少出血;(4)自体输血。本文综述了OTS中适用策略的有效性、安全性及建议,以及该外科专业中PBM方案开发与实施的障碍和要求。

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