Wu Chris Y, Archer Steven M, Kahana Alon
Department of Ophthalmology and Visual Sciences, WK Kellogg Eye Center, University of Michigan, Ann Arbor, MI.
Ophthalmic Plast Reconstr Surg. 2016 Jan-Feb;32(1):e7-8. doi: 10.1097/IOP.0000000000000399.
Carcinoid tumors are rare, slow-growing, low-grade neuroendocrine tumors with a propensity for orbital metastatic spread. The typical treatment paradigm for localized orbital disease involves excision, adjuvant radiotherapy, and/or receptor-targeted chemotherapy, followed by delayed evaluation for reconstructive strabismus surgery. We present a 58-year-old female patient with carcinoid tumor metastatic to the right inferior rectus muscle who presented with worsening binocular diplopia. The patient underwent coordinated "tag-team" orbital and strabismus surgeries that included excision of the right inferior rectus muscle to the annulus of Zinn followed immediately by reconstructive strabismus surgery. The patient required 1 additional strabismus surgery 1 year later. Follow up revealed no tumor recurrence at 4 years, and excellent binocular vision with good function. Deep orbital and strabismus surgeries, when performed simultaneously in a "tag-team" approach, may offer superior functional outcomes and improved patient quality of life, with expedited functional recovery. This approach may become a new treatment paradigm for surgical disease processes localized to the extraocular muscles.
类癌肿瘤罕见,生长缓慢,为低级别神经内分泌肿瘤,易于发生眼眶转移扩散。局限性眼眶疾病的典型治疗模式包括切除、辅助放疗和/或受体靶向化疗,随后延迟评估以进行斜视矫正手术。我们报告一名58岁女性患者,类癌转移至右下直肌,出现双眼复视加重。患者接受了协同的“接力”眼眶和斜视手术,包括将右下直肌切除至Zinn环,随后立即进行斜视矫正手术。患者在1年后还需要进行1次斜视手术。随访显示4年时无肿瘤复发,双眼视力良好,功能正常。采用“接力”方式同时进行深部眼眶和斜视手术,可能会提供更好的功能结果,改善患者生活质量,并加快功能恢复。这种方法可能会成为局限于眼外肌的外科疾病的一种新治疗模式。