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用于缓慢鞘内注射药物的系统的放射性核素评估

The radionuclide assessment of a system for slow intrathecal infusion of drugs.

作者信息

Hicks R J, Kalff V, Brazenor G, Rahmat H, Kelly M J

机构信息

Department of Nuclear Medicine, Alfred Hospital, Melbourne, Victoria, Australia.

出版信息

Clin Nucl Med. 1989 Apr;14(4):275-7. doi: 10.1097/00003072-198904000-00008.

DOI:10.1097/00003072-198904000-00008
PMID:2565175
Abstract

The authors describe a new radionuclide method for assessing the functional integrity of slow intrathecal infusion devices. Approximately 11 mCi (400 MBq) of Tc-99m DTPA is injected into the pump chamber. Early and delayed imaging of the pump, tubing, and spinal cerebrospinal fluid space is performed on a digital large-field-of-view gamma camera. The digitally displayed images are then reviewed by adjustment of the grey scale window. Four patients have had eight studies and in each case the result has been confirmed by surgical exploration or by clinical response to change in therapy.

摘要

作者描述了一种用于评估鞘内缓慢输注装置功能完整性的新放射性核素方法。将约11毫居里(400兆贝可)的锝-99m二乙三胺五乙酸注入泵腔。使用数字大视野伽马相机对泵、导管和脊髓脑脊液间隙进行早期和延迟成像。然后通过调整灰度窗口来查看数字显示的图像。4例患者进行了8次研究,在每种情况下,结果均通过手术探查或治疗改变后的临床反应得到证实。

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