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KIBRA genetic polymorphism and cognitive dysfunction in depression.

作者信息

Liu Jia Jia, Lavebratt Catharina, Lou Fenglan, Forsell Yvonne

机构信息

School of Nursing, Shandong University, Jinan 250012, China; Neurogenetics Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

Neurogenetics Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.

出版信息

Psychiatry Res. 2015 Mar 30;226(1):405-6. doi: 10.1016/j.psychres.2015.01.012. Epub 2015 Jan 24.

DOI:10.1016/j.psychres.2015.01.012
PMID:25656173
Abstract
摘要

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KIBRA genetic polymorphism and cognitive dysfunction in depression.KIBRA基因多态性与抑郁症中的认知功能障碍
Psychiatry Res. 2015 Mar 30;226(1):405-6. doi: 10.1016/j.psychres.2015.01.012. Epub 2015 Jan 24.
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Interactive effects of KIBRA and CLSTN2 polymorphisms on episodic memory in old-age unipolar depression.KIBRA基因和CLSTN2基因多态性对老年单相抑郁症情景记忆的交互作用。
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KIBRA genetic polymorphism influences episodic memory in later life, but does not increase the risk of mild cognitive impairment.KIBRA基因多态性影响晚年的情景记忆,但不会增加轻度认知障碍的风险。
J Cell Mol Med. 2008 Sep-Oct;12(5A):1672-6. doi: 10.1111/j.1582-4934.2008.00229.x. Epub 2008 Jan 11.
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Serum KIBRA mRNA and Protein Expression and Cognitive Functions in Depression.抑郁症患者血清中KIBRA mRNA和蛋白表达与认知功能
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Association of KIBRA rs17070145 polymorphism and episodic memory in individuals with severe TBI.KIBRA基因rs17070145多态性与重度创伤性脑损伤个体情景记忆的关联
Brain Inj. 2012;26(13-14):1658-69. doi: 10.3109/02699052.2012.700089. Epub 2012 Jul 13.
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Neurocognition and psychogenetic vulnerability in depression.抑郁症中的神经认知与心理遗传易感性
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Impact of common KIBRA allele on human cognitive functions.常见 KIBRA 等位基因对人类认知功能的影响。
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KIBRA: In the brain and beyond.KIBRA:在大脑内外的研究。
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Common exonic missense variants in the C2 domain of the human KIBRA protein modify lipid binding and cognitive performance.人类 KIBRA 蛋白 C2 结构域中的常见外显子错义变异可改变脂质结合和认知表现。
Transl Psychiatry. 2013 Jun 18;3(6):e272. doi: 10.1038/tp.2013.49.
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KIBRA polymorphism is associated with individual differences in hippocampal subregions: evidence from anatomical segmentation using high-resolution MRI.KIBRA 多态性与海马亚区的个体差异有关:使用高分辨率 MRI 进行解剖分割的证据。
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Chronic stress dysregulates the Hippo/YAP/14-3-3η pathway and induces mitochondrial damage in basolateral amygdala in a mouse model of depression.慢性应激会使 Hippo/YAP/14-3-3η 通路失调,并在抑郁小鼠模型的基底外侧杏仁核中诱导线粒体损伤。
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Deciphering the Effect of Different Genetic Variants on Hippocampal Subfield Volumes in the General Population.解析一般人群中不同遗传变异对海马亚区体积的影响。
Int J Mol Sci. 2023 Jan 6;24(2):1120. doi: 10.3390/ijms24021120.
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The Neuroprotection of KIBRA in Promoting Neuron Survival and Against Amyloid β-Induced Apoptosis.
KIBRA在促进神经元存活及抵抗淀粉样β蛋白诱导的细胞凋亡中的神经保护作用
Front Cell Neurosci. 2019 Apr 12;13:137. doi: 10.3389/fncel.2019.00137. eCollection 2019.
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KIBRA T allele influences memory performance and progression of cognitive decline: a 7-year follow-up study in subjective cognitive decline and mild cognitive impairment.KIBRA T 等位基因影响记忆表现和认知衰退的进展:一项在主观认知衰退和轻度认知障碍中进行的 7 年随访研究。
Neurol Sci. 2019 Aug;40(8):1559-1566. doi: 10.1007/s10072-019-03866-8. Epub 2019 Apr 5.
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Hippo Signaling: Emerging Pathway in Stress-Related Psychiatric Disorders?河马信号通路:应激相关精神障碍中的新兴通路?
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KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE ε4-positive cognitively normal adults with high Aβ-amyloid burden.KIBRA 与 APOE ε4 阳性认知正常但 Aβ-淀粉样蛋白负担高的成年人认知能力加速下降和海马萎缩有关。
Sci Rep. 2018 Feb 1;8(1):2034. doi: 10.1038/s41598-018-20513-y.
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Serum KIBRA mRNA and Protein Expression and Cognitive Functions in Depression.抑郁症患者血清中KIBRA mRNA和蛋白表达与认知功能
Med Sci Monit. 2016 Jan 15;22:152-60. doi: 10.12659/msm.895200.