Hemachandar R, Shanmugam Lokesh, Malepati Balakrishna, Venugopal Suresh
Department of Nephrology, Mahatma Gandhi Medical College and Research Institute, Puducherry, India.
Department of General Medicine, Mahatma Gandhi Medical College and Research Institute, Puducherry, India.
J Family Med Prim Care. 2014 Oct-Dec;3(4):464-6. doi: 10.4103/2249-4863.148153.
Vitamin D, the sunshine vitamin is now considered to be a hormone due to its important role in many physiological functions. Vitamin D deficiency has been associated with many disorders ranging from bone diseases, cardiovascular diseases to cancer. Hence, there is a recent surge in the empirical prescription of vitamin D for various disorders without documentation of vitamin D deficiency and monitoring the treatment. We report a case of iatrogenic hypercalcemia and acute kidney injury due to vitamin D toxicity after empirical and overzealous use of vitamin D and calcium supplements. We present this case to remind clinicians the importance of monitoring the patients treated with mega doses of vitamin D.
维生素D,即阳光维生素,由于其在许多生理功能中发挥重要作用,现在被视为一种激素。维生素D缺乏与多种疾病相关,从骨骼疾病、心血管疾病到癌症。因此,最近出现了一种现象,即在未记录维生素D缺乏情况和监测治疗的情况下,凭经验为各种疾病开具维生素D处方。我们报告一例因经验性且过度使用维生素D和钙补充剂导致维生素D中毒引起的医源性高钙血症和急性肾损伤病例。我们展示此病例以提醒临床医生监测接受大剂量维生素D治疗患者的重要性。