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触发式肌电图阈值能否确保椎弓根螺钉准确置入?一项关于诊断试验准确性的系统评价和荟萃分析。

Can triggered electromyography thresholds assure accurate pedicle screw placements? A systematic review and meta-analysis of diagnostic test accuracy.

作者信息

Lee Chang-Hyun, Kim Hyun-Woo, Kim Hong Rye, Lee Cheol-Young, Kim Jong-Hyun, Sala Francesco

机构信息

Department of Neurosurgery, Konyang University Hospital, Konyang University, College of Medicine, Daejeon, Republic of Korea.

Department of Neurosurgery, Konyang University Hospital, Konyang University, College of Medicine, Daejeon, Republic of Korea.

出版信息

Clin Neurophysiol. 2015 Oct;126(10):2019-25. doi: 10.1016/j.clinph.2014.11.026. Epub 2014 Dec 15.

Abstract

OBJECTIVE

Triggered electromyography (t-EMG) for pedicle screw placement was introduced to prevent the misplacement of screws; however, its diagnostic value is still debated. This study aimed to clarify the diagnostic value of t-EMG and to compare thresholds.

METHODS

We searched MEDLINE, EMBASE, and the Cochrane Library, and 179 studies were identified. Among them, 11 studies were finally enrolled. The pooled sensitivity, specificity, diagnostic odds ratio (DOR), and summary receiver operating characteristics (SROC) plots were analyzed.

RESULTS

The enrolled studies included 13,948 lumbar and 2070 thoracic screws. The overall summary sensitivity/specificity/DOR values of t-EMG were 0.55/0.97/42.16 in the lumbar spine and 0.41/0.95/14.52 in the thoracic spine, respectively, indicating a weak diagnostic value. However, subgroup analysis by each threshold value showed that the cutoff value of 8mA in the lumbar spine indicated high sensitivity (0.82), specificity (0.97), and DOR (147.95), thereby showing high diagnostic accuracy of identifying misplaced screws.

CONCLUSION

The most useful application of t-EMG may be as a warning tool for lumbar pedicle screw malpositioning in the presence of positive stimulation at a threshold of ⩽8mA.

SIGNIFICANCE

t-EMG by screw stimulation may be valuable in the lumbar region at a threshold of ⩽8mA.

摘要

目的

引入用于椎弓根螺钉置入的触发式肌电图(t-EMG)以防止螺钉误置;然而,其诊断价值仍存在争议。本研究旨在阐明t-EMG的诊断价值并比较阈值。

方法

我们检索了MEDLINE、EMBASE和Cochrane图书馆,共识别出179项研究。其中,最终纳入11项研究。分析了合并的敏感性、特异性、诊断比值比(DOR)和总结性受试者工作特征(SROC)曲线。

结果

纳入的研究包括13948枚腰椎螺钉和2070枚胸椎螺钉。t-EMG在腰椎的总体总结敏感性/特异性/DOR值分别为0.55/0.97/42.16,在胸椎分别为0.41/0.95/14.52,表明诊断价值较弱。然而,按每个阈值进行的亚组分析显示,腰椎8mA的临界值显示出高敏感性(0.82)、特异性(0.97)和DOR(147.95),从而显示出在识别误置螺钉方面具有高诊断准确性。

结论

t-EMG最有用的应用可能是作为一种警示工具,用于在阈值≤8mA出现阳性刺激时提示腰椎椎弓根螺钉位置异常。

意义

在阈值≤8mA时,通过螺钉刺激进行的t-EMG在腰椎区域可能具有价值。

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