• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

高氧会减小两栖类蝌蚪的肺大小,而不改变谷胱甘肽过氧化物酶或组织过氧化反应。

Hyperoxia decreases lung size of amphibian tadpoles without changing GSH-peroxidases or tissue peroxidation.

作者信息

Barja de Quiroga G, Lopez-Torres M, Gil P

机构信息

Department of Animal Biology-II (Animal Physiology), Faculty of Biology, Complutense University, Madrid, Spain.

出版信息

Comp Biochem Physiol A Comp Physiol. 1989;92(4):581-8. doi: 10.1016/0300-9629(89)90369-1.

DOI:10.1016/0300-9629(89)90369-1
PMID:2566423
Abstract
  1. During the development of D. pictus larvae (Amphibia) in normoxia, selenium (Se) GSH-Px increased whereas non-Se GSH-Px did not change. 2. Acclimation to 60 or 100% O2 did not change Se GSH-Px or non-Se GSH-Px. 3. Hyperoxia did not change tissue peroxidation (TBA-RS) confirming the good capacity of D. pictus tadpoles for O2-adaptation. 4. Since hyperoxic induction of catalase (CAT) has been previously described in D. pictus tadpoles, it is concluded that CAT is more important than both GSH-Px for the establishment of O2-adaptation. 5. Increases of Se GSH-Px, SOD and CAT, are probably important for adaptation to the change from aquatic to aerial environment during metamorphosis in normoxia. 6. Chronic exposure to 100% O2 enormously reduced the lung size of D. pictus larvae.
摘要
  1. 在常氧条件下黑斑侧褶蛙(两栖纲)幼体发育过程中,含硒谷胱甘肽过氧化物酶(Se GSH - Px)增加,而不含硒的谷胱甘肽过氧化物酶(非Se GSH - Px)没有变化。2. 适应60%或100%氧气环境并未改变Se GSH - Px或非Se GSH - Px。3. 高氧环境未改变组织过氧化(硫代巴比妥酸反应物,TBA - RS),证实黑斑侧褶蛙蝌蚪具有良好的氧气适应能力。4. 由于之前已描述过高氧对黑斑侧褶蛙蝌蚪过氧化氢酶(CAT)的诱导作用,得出结论:在建立氧气适应方面,CAT比两种谷胱甘肽过氧化物酶都更重要。5. 在常氧条件下,含硒谷胱甘肽过氧化物酶、超氧化物歧化酶(SOD)和过氧化氢酶的增加,可能对变态过程中从水生环境到陆生环境的转变适应很重要。6. 长期暴露于100%氧气环境会极大地减小黑斑侧褶蛙幼体的肺大小。

相似文献

1
Hyperoxia decreases lung size of amphibian tadpoles without changing GSH-peroxidases or tissue peroxidation.高氧会减小两栖类蝌蚪的肺大小,而不改变谷胱甘肽过氧化物酶或组织过氧化反应。
Comp Biochem Physiol A Comp Physiol. 1989;92(4):581-8. doi: 10.1016/0300-9629(89)90369-1.
2
Effect of hyperoxia acclimation on catalase and glutathione peroxidase activities and in vivo peroxidation products in various tissues of the frog Rana ridibunda perezi.高氧驯化对泽蛙不同组织中过氧化氢酶和谷胱甘肽过氧化物酶活性及体内过氧化产物的影响
J Exp Zool. 1988 Oct;248(1):7-18. doi: 10.1002/jez.1402480103.
3
Physiological significance of catalase and glutathione peroxidases, and in vivo peroxidation, in selected tissues of the toad Discoglossus pictus (Amphibia) during acclimation to normobaric hyperoxia.在常压高氧适应过程中,蟾蜍(盘舌蟾属)选定组织中过氧化氢酶和谷胱甘肽过氧化物酶的生理意义以及体内过氧化作用
J Comp Physiol B. 1988;158(5):583-90. doi: 10.1007/BF00692567.
4
Catalase is needed to avoid tissue peroxidation in Rana perezi in normoxia.
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1989;94(2):391-8. doi: 10.1016/0742-8413(89)90087-x.
5
mRNA expression of antioxidant enzymes (SOD, CAT and GSH-Px) and lipid peroxidative stress in liver of Atlantic salmon (Salmo salar) exposed to hyperoxic water during smoltification.在银化阶段暴露于高氧水中的大西洋鲑(Salmo salar)肝脏中抗氧化酶(超氧化物歧化酶、过氧化氢酶和谷胱甘肽过氧化物酶)的mRNA表达及脂质过氧化应激。
Comp Biochem Physiol C Toxicol Pharmacol. 2005 Jul;141(3):314-23. doi: 10.1016/j.cbpc.2005.07.009.
6
Endotoxin protects selenium-deficient rats from hyperoxia.内毒素可保护缺硒大鼠免受高氧损伤。
J Lab Clin Med. 1984 Jan;103(1):143-51.
7
Non-selenium-dependent glutathione peroxidase activity in rat lung: association with lung glutathione S-transferase activity and the effects of hyperoxia.大鼠肺中不依赖硒的谷胱甘肽过氧化物酶活性:与肺谷胱甘肽S-转移酶活性的关联及高氧的影响
Toxicol Appl Pharmacol. 1983 May;68(3):399-404. doi: 10.1016/0041-008x(83)90284-3.
8
Glutathione redox system, GSH-Px activity and lipid peroxidation (LPO) levels in tadpoles of R.r.ridibunda and B.viridis.赤蛙科泽蛙蝌蚪和绿蟾蜍蝌蚪体内的谷胱甘肽氧化还原系统、谷胱甘肽过氧化物酶(GSH-Px)活性及脂质过氧化(LPO)水平
Cell Biochem Funct. 2003 Mar;21(1):75-9. doi: 10.1002/cbf.998.
9
Different levels of hyperoxia reversibly induce catalase activity in amphibian tadpoles.不同程度的高氧可在两栖类蝌蚪中可逆地诱导过氧化氢酶活性。
Free Radic Biol Med. 1987;3(2):137-46. doi: 10.1016/s0891-5849(87)80009-6.
10
Response of glutathione peroxidase and catalase to excess dietary iron in rats.
J Nutr. 1981 Dec;111(12):2195-202. doi: 10.1093/jn/111.12.2195.

引用本文的文献

1
Comparison of hypoxia- and hyperoxia-induced alteration of epigene expression pattern in lungs of Pleurodeles waltl and Mus musculus.比较 Hypoxia(缺氧)和 Hyperoxia(富氧)诱导的 Pleurodeles waltl 和 Mus musculus 肺部表观遗传表达模式的改变。
PLoS One. 2024 Feb 28;19(2):e0299661. doi: 10.1371/journal.pone.0299661. eCollection 2024.
2
Plasticity of lung development in the amphibian, Xenopus laevis.两栖动物非洲爪蟾肺发育的可塑性。
Biol Open. 2013 Dec 15;2(12):1324-35. doi: 10.1242/bio.20133772.