Park Young-Wook, Lee Woo-Young, Kwon Kwang-Jun, Kim Seong-Gon, Lee Suk-Keun
Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University, 7 jukheon-gil, Gangneung, 210-702 Gangwondo Republic of Korea.
Department of Oral Pathology, College of Dentistry, Gangneung-Wonju National University, Gangneung, Korea.
Maxillofac Plast Reconstr Surg. 2015 Feb 5;37(1):4. doi: 10.1186/s40902-015-0005-5. eCollection 2015 Dec.
Osteochondroma is rarely reported in the maxillofacial region; however, it is prevalent in the mandibular condyle. This slowly growing tumor may lead to malocclusion and facial asymmetry. A 39-year-old woman complained of gradual development of anterior and posterior unilateral crossbite, which resulted in facial asymmetry. A radiological study disclosed a large tumor mass on the top of the left mandibular condyle. This bony tumor was surgically removed through condylectomy and the remaining condyle head was secured. Subsequently, bimaxillary orthognathic surgery was performed to correct facial asymmetry and malocclusion. Pathological diagnosis was osteochondroma; immunohistochemistry showed that the tumor exhibited a conspicuous expression of BMP-4 and BMP-2 but rarely expression of PCNA. There was no recurrence at least for 1 year after the operation. Patient's functional and esthetic rehabilitation was uneventful.
骨软骨瘤在颌面部区域很少见；然而，它在下颌髁突很常见。这种生长缓慢的肿瘤可能导致错牙合畸形和面部不对称。一名39岁女性主诉逐渐出现单侧前后牙反牙合，导致面部不对称。影像学检查发现左下颌髁突顶部有一个大的肿瘤块。通过髁突切除术手术切除了这个骨肿瘤，并固定了剩余的髁突头。随后，进行了双颌正颌手术以纠正面部不对称和错牙合畸形。病理诊断为骨软骨瘤；免疫组织化学显示肿瘤显著表达BMP - 4和BMP - 2，但PCNA表达很少。术后至少1年无复发。患者的功能和美学康复过程顺利。
