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优势半球多处海马横断术后Wada试验的病例报告:注射异戊巴比妥后意识模糊的病理生理学

A case report of a Wada test after dominant hemisphere multiple hippocampal transections: Pathophysiology of confusion after amobarbital injection.

作者信息

Landazuri Patrick, Miller Jonathan, Lüders Hans

机构信息

University Hospitals, Case Medical Center, Department of Neurology, Epilepsy Division, 11100 Euclid Avenue, Lakeside 3200, Cleveland, OH, USA ; University of Kansas Medical Center, Department of Neurology, 3599 Rainbow Blvd, Kansas City, KS 66103, USA.

University Hospitals, Case Medical Center, Department of Neurosurgery, 11100 Euclid Avenue, Lakeside 3200, Cleveland, OH 44106, USA.

出版信息

Epilepsy Behav Case Rep. 2014 Jun 14;2:130-2. doi: 10.1016/j.ebcr.2014.05.003. eCollection 2014.

Abstract

Dialepsis is defined as a predominant alteration of consciousness with preservation of motor tone and the ability to perform movements. While dialepsis is a common feature of both focal and generalized epilepsies, its precise symptomatogenic zone and pathogenesis remain undefined. This case report describes a patient who underwent intracarotid amobarbital procedures before and after dominant hemisphere multiple hippocampal transections. From our observations, we propose a possible pathogenesis for the generation of dialeptic seizures.

摘要

意识错乱被定义为意识的主要改变,同时保留运动张力和执行运动的能力。虽然意识错乱是局灶性和全身性癫痫的常见特征,但其确切的致症状区和发病机制仍不明确。本病例报告描述了一名患者,其在优势半球多次海马横断术前后接受了颈动脉内异戊巴比妥试验。根据我们的观察,我们提出了意识错乱性癫痫发作产生的一种可能发病机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d75b/4307959/9f651f17ecd9/gr1.jpg

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