Kratz Thomas, Dette Frank, Schmitt Jan, Wiesmann Thomas, Wulf Hinnerk, Zoremba Martin
Department of Anesthesia and Intensive Care Medicine, University Hospital, Philipps-University of Marburg, Marburg, Germany.
Department of Anesthesia and Intensive Care Medicine, Clinique Bénigne Joly, Talant, France.
Technol Health Care. 2015;23(3):313-22. doi: 10.3233/THC-150898.
Adequate pain management is essential for preventing hemodynamic instability which can affect the perfusion of vital organs during the perioperative period, particularly in geriatric patients. For hip arthroplasty, peripheral nerve block is frequently used, limiting the adverse effects of opioid and non-opioid analgesics.
The aim was to survey the impact of a supplementary single shot femoral nerve block (FNB) on hemodynamic stability and pain level.
After registration at German Clinical Trial Register (DRKS-ID): DRKS00000752. and Ethics Committee approval (University Hospital of Marburg), 80 patients who underwent elective hip surgery were included. Half of them were randomly assigned to receive a FNB followed by general anesthesia; a control group received only general anesthesia as standard procedure (STD). Blood pressure and heart rate were measured and recorded every five minutes during surgery and stay at the postanesthesia care unit (PACU).
Fifty-two patients were included for statistical analysis. The FNB group had significantly lower systolic blood pressures during and after surgery and lower diastolic blood pressure postoperatively, heart rate, as well as opioid and non-steroidal anti-inflammatory consumption.
Femoral nerve block improved perioperative hemodynamic stability mostly likely attributable to an overall reduced sympathico adrenergic tone.
充分的疼痛管理对于预防血流动力学不稳定至关重要,这可能会在围手术期影响重要器官的灌注,尤其是老年患者。对于髋关节置换术,经常使用外周神经阻滞,以限制阿片类和非阿片类镇痛药的不良反应。
目的是调查单次补充股神经阻滞(FNB)对血流动力学稳定性和疼痛程度的影响。
在德国临床试验注册中心(DRKS-ID:DRKS00000752)注册并获得马尔堡大学医院伦理委员会批准后,纳入80例行择期髋关节手术的患者。其中一半患者被随机分配接受FNB,然后进行全身麻醉;对照组仅接受作为标准程序(STD)的全身麻醉。在手术期间以及在麻醉后护理单元(PACU)停留期间,每五分钟测量并记录一次血压和心率。
52例患者纳入统计分析。FNB组在手术期间和术后的收缩压显著较低,术后舒张压、心率以及阿片类和非甾体抗炎药的消耗量也较低。
股神经阻滞改善了围手术期的血流动力学稳定性,这很可能归因于交感肾上腺素能张力的总体降低。