Müller E E
Department of Pharmacology, Chemotherapy and Toxicology, University of Milan, Italy.
Pharmacol Res. 1989 Jan-Feb;21(1):75-85. doi: 10.1016/1043-6618(89)90125-4.
It is now indisputably established that a cohort of neurotransmitters and neuropeptides affect the secretion of anterior pituitary hormones by modulating the functional activity of specific hypophysiotropic regulatory hormones. Some salient aspects of the role of gamma-aminobutyric acid in the control of prolactin secretion and of catecholamines and acetylcholine in the control of growth hormone secretion are reviewed, also underlying some diagnostic and therapeutic applications of the new findings in neuroendocrine disorders.
现已无可争议地确定,一组神经递质和神经肽通过调节特定促垂体调节激素的功能活性来影响垂体前叶激素的分泌。本文综述了γ-氨基丁酸在催乳素分泌控制中的作用以及儿茶酚胺和乙酰胆碱在生长激素分泌控制中的作用的一些显著方面,同时也阐述了这些新发现在内分泌疾病诊断和治疗中的一些应用。