噬血细胞性淋巴组织细胞增生症（HLH）病例报告。

A case report of hemophagocytic lymphohistiocytosis (HLH).

作者信息

Rajadhyaksha Anjali, Sonawale Archana, Agrawal Ajay, Ahire Kiran, Kawale Juhi

出版信息

J Assoc Physicians India. 2014 Jul;62(7):637-41.

PMID:25672045

Abstract

Hemophagocytic lymphohistiocytosis (HLH), is an uncommon, life-threatening hyperinflammatory syndrome caused by severe hypercytokinemia with excessive activation of lymphocytes and macrophages due to a highly stimulated but ineffective immune process. We report a case of Hemophagocytic Lymphohistiocytosis in a 15 year old boy presenting with fever, lymphadenopathy and pancytopenia due to infection caused by Klebsiella Pneumoniae and Acinetobacter.

摘要

噬血细胞性淋巴组织细胞增生症（HLH）是一种罕见的、危及生命的高炎症综合征，由严重的高细胞因子血症引起，由于免疫过程受到高度刺激但无效，导致淋巴细胞和巨噬细胞过度活化。我们报告一例15岁男孩的噬血细胞性淋巴组织细胞增生症，该男孩因肺炎克雷伯菌和不动杆菌感染出现发热、淋巴结病和全血细胞减少。