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四肢骨骼骨折的流行病学:来自诺丁汉骨折联络服务中心数据的横断面分析

Epidemiology of appendicular skeletal fractures: a cross-sectional analysis of data from the Nottingham Fracture Liaison Service.

作者信息

Ong Terence, Sahota Opinder, Marshall Lindsey

机构信息

Department of Healthcare for Older Person, Queens Medical Centre, Derby Road, Nottingham, NG7 2UH, UK,

出版信息

J Orthop Sci. 2015 May;20(3):517-21. doi: 10.1007/s00776-015-0700-1. Epub 2015 Feb 13.

Abstract

BACKGROUND

The aim of this study is to describe the population-based age and gender appendicular skeletal fracture incidence in Nottinghamshire, a medium-size health county in the UK.

METHOD

Data were analysed from the Nottingham Fracture Liaison Service Database over 4 years (2008-2011) on patients over 50 years of age. ICD-9 codes were used to classify fracture sites. Population figures from the Office of National Statistics were used to calculate fracture incidence rates per 10,000 population. Those aged 75 years and older were used to define the elderly population.

RESULTS

A total of 7,767 patients with 7,806 fractures presented over this time period. The overall incidence in males was 24/10,000 and in females 73/10,000. The incidence of fracture increased with age in females (R (2) = 0.90) compared to males (R (2) = 0.06). The over 75 population is more likely to fracture their wrist (OR 1.36, 95% CI 1.24-1.50, p < 0.01), humerus (OR 1.87, 95% CI 1.65-2.12, p < 0.01) and clavicle (OR 1.34, 95% CI 1.07-1.69, p = 0.011) compared to other fractures. There was linearity with radius/ulna and humerus fractures with age (R (2) = 0.92, R (2) = 0.97, respectively).

CONCLUSION

The incidence of appendicular skeletal fractures is high especially in the elderly female population with fractures of the upper limb more common. With an ageing population these numbers are projected to increase and therefore effective strategies to prevent falls and osteoporosis are clearly necessary.

摘要

背景

本研究旨在描述英国中等规模健康郡诺丁汉郡基于人群的年龄和性别上肢骨骼骨折发病率。

方法

对诺丁汉骨折联络服务数据库中4年(2008 - 2011年)50岁以上患者的数据进行分析。使用国际疾病分类第九版(ICD - 9)编码对骨折部位进行分类。利用国家统计局的人口数据计算每10000人口的骨折发病率。75岁及以上人群被定义为老年人群。

结果

在此期间,共有7767例患者发生了7806处骨折。男性的总体发病率为24/10000,女性为73/10000。与男性(R² = 0.06)相比,女性骨折发病率随年龄增长(R² = 0.90)。与其他骨折相比,75岁及以上人群更易发生手腕骨折(比值比[OR] 1.36,95%置信区间[CI] 1.24 - 1.50,p < 0.01)、肱骨骨折(OR 1.87,95% CI 1.65 - 2.12,p < 0.01)和锁骨骨折(OR 1.34,95% CI 1.07 - 1.69,p = 0.011)。桡骨/尺骨和肱骨骨折发病率与年龄呈线性关系(分别为R² = 0.92,R² = 0.97)。

结论

上肢骨骼骨折发病率较高,尤其是老年女性人群,上肢骨折更为常见。随着人口老龄化,预计这些数字将会增加,因此显然需要有效的预防跌倒和骨质疏松的策略。

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