Linkage data on affective disorders in an epidemiologic context.
作者信息
Gershon E S, Goldin L R
机构信息
Clinical Neurogenetics Branch, National Institute of Mental Health, Bethesda, Maryland 20892.
出版信息
Genet Epidemiol. 1989;6(1):201-9. doi: 10.1002/gepi.1370060136.
PMID:2567258
Abstract
Recent data on chromosomal linkage markers in affective disorders indicate that single locus inheritance is involved in these disorders. The presence of a single locus has not been detectable using segregation analysis on family study data from large populations, possibly because of both heterogeneity and birth cohort and sex differences in diagnostic frequencies.
摘要
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