Bakian Amanda V, Huber Rebekah S, Coon Hilary, Gray Douglas, Wilson Phillip, McMahon William M, Renshaw Perry F
Am J Epidemiol. 2015 Mar 1;181(5):295-303. doi: 10.1093/aje/kwu341. Epub 2015 Feb 10.
Research into environmental factors associated with suicide has historically focused on meteorological variables. Recently, a heightened risk of suicide related to short-term exposure to airborne particulate matter was reported. Here, we examined the associations between short-term exposure to nitrogen dioxide, particulate matter, and sulfur dioxide and completed suicide in Salt Lake County, Utah (n = 1,546) from 2000 to 2010. We used a time-stratified case-crossover design to estimate adjusted odds ratios for the relationship between suicide and exposure to air pollutants on the day of the suicide and during the days preceding the suicide. We observed maximum heightened odds of suicide associated with interquartile-range increases in nitrogen dioxide during cumulative lag 3 (average of the 3 days preceding suicide; odds ratio (OR) = 1.20, 95% confidence interval (CI): 1.04, 1.39) and fine particulate matter (diameter ≤2.5 μm) on lag day 2 (day 2 before suicide; OR = 1.05, 95% CI: 1.01, 1.10). Following stratification by season, an increased suicide risk was associated with exposure to nitrogen dioxide during the spring/fall transition period (OR = 1.35, 95% CI: 1.09, 1.66) and fine particulate matter in the spring (OR = 1.28, 95% CI: 1.01, 1.61) during cumulative lag 3. Findings of positive associations between air pollution and suicide appear to be consistent across study locations with vastly different meteorological, geographical, and cultural characteristics.
与自杀相关的环境因素研究历来集中在气象变量上。最近,有报告称短期接触空气中的颗粒物会增加自杀风险。在此,我们研究了2000年至2010年期间,犹他州盐湖县(n = 1546)短期接触二氧化氮、颗粒物和二氧化硫与自杀身亡之间的关联。我们采用时间分层病例交叉设计,以估计自杀当天及自杀前几天自杀与接触空气污染物之间关系的调整比值比。我们观察到,在累积滞后3天(自杀前3天的平均值)二氧化氮四分位间距增加时,自杀几率最高(比值比(OR)= 1.20,95%置信区间(CI):1.04,1.39),以及在滞后第2天(自杀前第2天)细颗粒物(直径≤2.5μm)增加时(OR = 1.05,95% CI:1.01,1.10)。按季节分层后,在春季/秋季过渡期接触二氧化氮(OR = 1.35,95% CI:1.09,1.66)以及在累积滞后3天的春季接触细颗粒物(OR = 1.28,95% CI:1.01,1.61)与自杀风险增加相关。空气污染与自杀之间存在正相关的研究结果在气象、地理和文化特征差异极大的不同研究地点似乎是一致的。