Environmental Epidemiology Program, Utah Department of Health, Salt Lake City, Utah, USA.
Environ Health Perspect. 2012 Oct;120(10):1385-90. doi: 10.1289/ehp.1104349. Epub 2012 Jul 11.
Winter temperature inversions-layers of air in which temperature increases with altitude-trap air pollutants and lead to higher pollutant concentrations. Previous studies have evaluated associations between pollutants and emergency department (ED) visits for asthma, but none have considered inversions as independent risk factors for ED visits for asthma.
We aimed to assess associations between winter inversions and ED visits for asthma in Salt Lake County, Utah.
We obtained electronic records of ED visits for asthma and data on inversions, weather, and air pollutants for Salt Lake County, Utah, during the winters of 2003 through 2004 to 2007 through 2008. We identified 3,425 ED visits using a primary diagnosis of asthma. We used a time-stratified case-crossover design, and conditional logistic regression models to calculate odds ratios (ORs) and 95% confidence intervals (CIs) to estimate rate ratios of ED visits for asthma in relation to inversions during a 4-day lag period and prolonged inversions. We evaluated interactions between inversions and weather and pollutants.
After adjusting for dew point and mean temperatures, the OR for ED visits for asthma associated with inversions 0-3 days before the visit compared with no inversions during the lag period was 1.14 (95% CI: 1.00, 1.30). The OR for each 1-day increase in the number of inversion days during the lag period was 1.03 (95% CI: 1.00, 1.07). Associations were only apparent when PM10 and maximum and mean temperatures were above median levels.
Our results provide evidence that winter inversions are associated with increased rates of ED visits for asthma.
冬季逆温——温度随高度升高而升高的空气层——会困住空气污染物,导致污染物浓度升高。先前的研究已经评估了污染物与哮喘急诊就诊之间的关联,但没有研究将逆温作为哮喘急诊就诊的独立危险因素。
我们旨在评估犹他州盐湖县冬季逆温与哮喘急诊就诊之间的关联。
我们获得了犹他州盐湖县 2003 年至 2004 年至 2007 年至 2008 年冬季哮喘急诊就诊和逆温、天气以及空气污染物的电子记录。我们使用哮喘的主要诊断识别了 3425 次急诊就诊。我们使用时间分层病例交叉设计和条件逻辑回归模型,计算了在 4 天滞后期内以及在长时间逆温期间哮喘急诊就诊与逆温相关的比值比(OR)和 95%置信区间(CI),以估计哮喘急诊就诊的发生率比。我们评估了逆温和天气以及污染物之间的相互作用。
在调整露点和平均温度后,与滞后期内没有逆温相比,就诊前 0-3 天出现逆温时哮喘急诊就诊的 OR 为 1.14(95%CI:1.00,1.30)。滞后期内逆温天数每增加 1 天,OR 为 1.03(95%CI:1.00,1.07)。只有当 PM10 以及最高和平均温度高于中位数水平时,关联才明显。
我们的研究结果提供了证据,表明冬季逆温与哮喘急诊就诊率升高有关。