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使用异氟烷和低温治疗超难治性癫痫持续状态

Management of super-refractory status epilepticus with isoflurane and hypothermia.

作者信息

Zhumadilov Agzam, Gilman Charles P, Viderman Dmitriy

机构信息

Republican Research Center for Emergency Care , Astana , Kazakhstan.

School of Science and Technology, Nazarbayev University , Astana , Kazakhstan.

出版信息

Front Neurol. 2015 Jan 28;5:286. doi: 10.3389/fneur.2014.00286. eCollection 2014.

DOI:10.3389/fneur.2014.00286
PMID:25674075
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4309114/
Abstract

Super-refractory status epilepticus (SRSE) is defined as status epilepticus that continues 24 h or more after the onset of anesthesia, and includes those cases in which epilepsy is recurrent upon treatment reduction. We describe the presentation and successful management of a male patient with SRSE using the inhaled anesthetic isoflurane, and mild hypothermia (HT). The potential utility of combined HT and volatile anesthesia is discussed.

摘要

超难治性癫痫持续状态(SRSE)被定义为在麻醉开始后持续24小时或更长时间的癫痫持续状态,包括那些在减药治疗时癫痫复发的病例。我们描述了一名使用吸入麻醉药异氟烷和轻度低温(HT)治疗的SRSE男性患者的临床表现及成功治疗过程。并讨论了联合HT和挥发性麻醉的潜在效用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/703c/4309114/c7f9679427d4/fneur-05-00286-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/703c/4309114/c7f9679427d4/fneur-05-00286-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/703c/4309114/c7f9679427d4/fneur-05-00286-g001.jpg

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Therapeutic brain hypothermia, its mechanisms of action, and its prospects as a treatment for epilepsy.
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