Scaravilli Gabriele, Rossi Roberto, Artiaco Stefano, Merolla Giovanni
Orthopedics and Trauma Clinic, Second University of Naples - Naples - Italy.
U.O.C Muscoloskeletal Traumatology, U.O.D. Microsurgery, C.T.O. Hospital, Torino, Italy.
Transl Med UniSa. 2014 Dec 19;11:63-8. eCollection 2015 Jan-Apr.
Neurofibromatosis type 1 (NF1) is a disease characterized by increased tumorigenesis susceptibility, caused by mutations of the oncosuppressor gene NF1. The glomus tumor (GT) is a rare, very painful mesenchymal neoplasm, arising from the glomus body. In recent years, it has been highlighted the association between NF1 and GT. We report a case of a man aged 65 years, suffering from NF1, with intense pain at the thenar eminence of the right hand, successfully treated with the excision of the mass.
1型神经纤维瘤病（NF1）是一种因肿瘤抑制基因NF1突变导致肿瘤发生易感性增加的疾病。血管球瘤（GT）是一种罕见的、疼痛剧烈的间叶性肿瘤，起源于血管球。近年来，NF1与GT之间的关联受到了关注。我们报告一例65岁男性患者，患有NF1，右手鱼际处剧痛，经肿块切除后成功治愈。
