Ming Ming, Wang Zhen G, Li DaCheng, Wu FengYu, Liu SiMin, Shi Bin, Xue Wei
From the Hospital of Qingdao University, Qingdao, China (MM, ZGW, DL, FY, SL, BS, WX).
Medicine (Baltimore). 2015 Feb;94(6):e531. doi: 10.1097/MD.0000000000000531.
Fluorine 18-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) imaging has been widely used to diagnose many types of tumors. However, many factors can affect the accuracy of standardized uptake values (SUVs). In this study, we aimed to explore the applications of corrected SUVs in the diagnosis of peripheral solitary pulmonary lesions.A retrospective study was undertaken in 69 patients with peripheral solitary pulmonary lesions. Whole-body PET/CT was acquired approximately 60 min after F-FDG injection. The lesions were found to be malignant in 57 cases and benign in 12 cases. Of the 69 cases, 68 were correctly diagnosed, and only 1 was misdiagnosed by the corrected SUVs. The diagnostic accuracy rate was 98.5%. The sensitivity, specificity, positive predictive value, and negative predictive value of the corrected SUV were 100%, 91.7%, 98.3%, and 100%, respectively.F-FDG PET/CT with corrected SUVs is of great value for improving diagnostic accuracy in peripheral lung lesions.
氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描（F-FDG PET/CT）成像已被广泛用于多种肿瘤的诊断。然而，许多因素会影响标准化摄取值（SUV）的准确性。在本研究中，我们旨在探讨校正SUV在周围型孤立性肺病变诊断中的应用。
对69例周围型孤立性肺病变患者进行了一项回顾性研究。在注射F-FDG后约60分钟进行全身PET/CT检查。发现病变为恶性57例，良性12例。69例中，68例诊断正确，校正SUV仅误诊1例。诊断准确率为98.5%。校正SUV的敏感性、特异性、阳性预测值和阴性预测值分别为100%、91.7%、98.3%和100%。
校正SUV的F-FDG PET/CT对提高周围型肺部病变的诊断准确性具有重要价值。
