Li Peng, Zhang Xu, Luo Rui-Hua, Zhao Ming, Liu Shan-Ting, Du Wei, Qi Jin-Xing
From the Department of Head Neck & Thyroid Surgery, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, Henan, P.R. China.
J Craniofac Surg. 2015 Mar;26(2):e75-8. doi: 10.1097/SCS.0000000000001280.
The purpose of our study was to investigate (by postal questionnaire) the long-term quality of life (QoL) in Chinese patients who have had resections of head and neck cancer and immediate reconstruction by radial forearm free flaps. We performed a retrospective questionnaire survey and case series in the Affiliated Tumor Hospital of Zhengzhou University. The subjects were consecutive patients treated for head and neck cancers during a 13-year period. The patients completed the University of Washington Quality of Life (version 4) questionnaires. Among the 178 patients treated during the course of 13 years, 87 were alive and disease free. Fifty-six (64.4%) of the 87 questionnaires were returned. The mean follow-up duration was 7.9 years (range, 3-13 y). Of the 12 disease-specific domains on the University of Washington Quality of Life, the best-scoring domain was pain, followed by mood, anxiety, and shoulder, whereas the lowest scores were for saliva, taste, and speech. The domains considered as the most important were saliva, speech, and taste. We conclude that the radial forearm free flap for the reconstruction of defects of the head and neck after resection for cancer significantly influenced the patients' long-term QoL.
我们研究的目的是（通过邮寄问卷调查）调查接受头颈癌切除及前臂桡侧游离皮瓣即刻重建的中国患者的长期生活质量（QoL）。我们在郑州大学附属肿瘤医院进行了一项回顾性问卷调查和病例系列研究。研究对象为在13年期间接受头颈癌治疗的连续患者。患者完成了华盛顿大学生活质量问卷（第4版）。在13年期间接受治疗的178例患者中，87例存活且无疾病。87份问卷中有56份（64.4%）被返还。平均随访时间为7.9年（范围3 - 13年）。在华盛顿大学生活质量问卷的12个疾病特定领域中，得分最高的领域是疼痛，其次是情绪、焦虑和肩部，而得分最低的是唾液、味觉和言语。被认为最重要的领域是唾液、言语和味觉。我们得出结论，前臂桡侧游离皮瓣用于癌症切除术后头颈缺损的重建显著影响了患者的长期生活质量。
