Schetgen M
Rev Med Brux. 2014 Sep;35(4):325-8.
In 2007, due to the number of invasive pneumococcal infections and resistance to antibiotics, Belgium introduced juvenile anti-pneumococcal vaccination, recommending the 7-valent conjugate vaccine which provides better immune protection and memory than the 23-valent one for adults. In 2011, due to the increase in non-vaccine serotypes, the decision was taken to replace the 7-valent vaccine with a conjugate 13-valent one. Henceforth, essentially high-risk adults are given a 13-valent vaccine followed 8 weeks later by a 23-valent one, with a 23-valent booster every 5 years.
2007年,由于侵袭性肺炎球菌感染数量以及对抗生素的耐药性问题,比利时推出了青少年抗肺炎球菌疫苗接种计划,推荐使用7价结合疫苗,该疫苗相比成人用的23价疫苗能提供更好的免疫保护和免疫记忆。2011年,由于非疫苗血清型的增加,决定用13价结合疫苗取代7价疫苗。此后,基本上高危成年人先接种13价疫苗,8周后再接种23价疫苗,每5年进行一次23价疫苗加强接种。