Pietrygal Marek, Brazert Jacek, Wender-Ozegowskal Ewa, Zawiejska Agnieszka, Brazert Maciej, Dubiel Mariusz, Gudmundsson Saemundur
Ginekol Pol. 2014 Nov;85(11):810-4.
A voluminous umbilical cord has been described in diabetic pregnancies. The aim of this studywas to see if measurements of cord diameters might be of value in the evaluation of diabetic pregnancies and especially those suspected of a large for gestational age (LGA) fetus.
In an observational, prospective study umbilical cord areas and vessel diameters were measured between gestational age of 22 and 40 weeks in transverse ultrasound images of the central part of the cord in 141 normal and 135 diabetic pregnancies of which 30 were suspected of being LGA. Wharton's jelly area was calculated by subtracting the vessel area from the total transverse cord area. Normal reference curves were constructed for gestational age.
Umbilical cord and Wharton's jelly areas increased with gestation. The vessel area leveled out at 32-33 weeks of gestation and the umbilical vein area decreased after 36 weeks of gestation. The umbilical cord parameters in diabetic pregnancies did not differ from controls. Cord areas were enlarged in 1/3 of the LGA fetuses.
Umbilical cord area measurements are of limited value for the evaluation of diabetic pregnancies suspected having a LGA-fetus.
已有文献报道糖尿病妊娠时脐带粗大。本研究旨在探讨测量脐带直径对评估糖尿病妊娠,尤其是怀疑为大于胎龄(LGA)胎儿的糖尿病妊娠是否有价值。
在一项观察性前瞻性研究中,对141例正常妊娠和135例糖尿病妊娠(其中30例怀疑为LGA)在孕22至40周时脐带中央部分的横向超声图像测量脐带面积和血管直径。通过从脐带总横截面积中减去血管面积来计算华通胶面积。构建了胎龄的正常参考曲线。
脐带和华通胶面积随孕周增加。血管面积在妊娠32 - 33周时趋于平稳,脐静脉面积在妊娠36周后下降。糖尿病妊娠的脐带参数与对照组无差异。1/3的LGA胎儿脐带面积增大。
脐带面积测量对于评估怀疑有LGA胎儿的糖尿病妊娠价值有限。