De Natale G, De Natale F, Marino A
Clin Ter. 1989 Apr 15;129(1):3-16.
Drugs used in the management of peptic ulcer are reviewed with special attention to the possibilities offered by H2 receptor antagonists. In this context, histaminergic transmission and distribution of H2 receptors are briefly reviewed. Among other substances, special interest has been raised by H+ and K+-dependent ATPase inhibitors; the most recently introduced derivatives of these substances which are as yet in the experimental stage, are also listed.
本文对用于治疗消化性溃疡的药物进行了综述,特别关注了H2受体拮抗剂的应用前景。在此背景下,简要回顾了组胺能传递及H2受体的分布情况。在其他物质中,H+和K+-依赖性ATP酶抑制剂引发了特别关注;文中还列出了这些物质中最新推出的、仍处于实验阶段的衍生物。