非结核分枝杆菌肺病的微生物学诊断。

Microbiological diagnosis of nontuberculous mycobacterial pulmonary disease.

机构信息

Department of Medical Microbiology (777), Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

出版信息

Clin Chest Med. 2015 Mar;36(1):43-54. doi: 10.1016/j.ccm.2014.11.005. Epub 2014 Dec 18.

DOI:10.1016/j.ccm.2014.11.005

PMID:25676518

Abstract

Pulmonary disease is by far the most frequent disease caused by nontuberculous mycobacteria (NTM). To diagnose NTM pulmonary disease (NTM-PD), patients should have symptoms and radiologic signs suggestive of NTM-PD, and cultures of multiple respiratory tract samples must grow the same NTM species. Thus, the microbiological laboratory has a central role in the diagnosis of NTM-PD. This review summarizes currently available data on techniques involved in the microbiological diagnosis of NTM-PD, and aims to provide a framework for optimal microbiological diagnosis.

摘要

肺部疾病是迄今为止由非结核分枝杆菌（NTM）引起的最常见疾病。为了诊断非结核分枝杆菌肺病（NTM-PD），患者应有提示 NTM-PD 的症状和影像学征象，且多个呼吸道样本的培养必须生长出相同的 NTM 物种。因此，微生物实验室在 NTM-PD 的诊断中起着核心作用。这篇综述总结了目前关于 NTM-PD 微生物学诊断中涉及的技术的可用数据，并旨在为最佳微生物学诊断提供一个框架。