Capstick Toby, Hurst Rhys, Keane Jennie, Musaddaq Besma
St James's University Hospital, Leeds LS9 7TF, UK.
Royal Papworth Hospital NHS Foundation Trust, Cambridge CB2 0AY, UK.
Pharmacy (Basel). 2024 Aug 21;12(4):126. doi: 10.3390/pharmacy12040126.
Nontuberculous mycobacterial pulmonary disease (NTM-PD) results from opportunistic lung infections by mycobacteria other than or species. Similar to many other countries, the incidence of NTM-PD in the United Kingdom (UK) is on the rise for reasons that are yet to be determined. Despite guidelines established by the American Thoracic Society (ATS), the Infectious Diseases Society of America, and the British Thoracic Society, NTM-PD diagnosis and management remain a significant clinical challenge. In this review article, we comprehensively discuss key challenges in NTM-PD diagnosis and management, focusing on the UK healthcare setting. We also propose countermeasures to overcome these challenges and improve the detection and treatment of patients with NTM-PD.
非结核分枝杆菌肺病（NTM-PD）是由除结核分枝杆菌复合群或麻风分枝杆菌以外的分枝杆菌引起的机会性肺部感染所致。与许多其他国家一样，英国（UK）的NTM-PD发病率正在上升，原因尚待确定。尽管美国胸科学会（ATS）、美国传染病学会和英国胸科学会制定了相关指南，但NTM-PD的诊断和管理仍然是一项重大的临床挑战。在这篇综述文章中，我们全面讨论了NTM-PD诊断和管理中的关键挑战，重点关注英国的医疗环境。我们还提出了应对这些挑战的对策，以改善NTM-PD患者的检测和治疗。
