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伴有肾脏受累的罕见狼疮样颧部皮疹:血管免疫母细胞性T细胞淋巴瘤——病例报告

A strange lupus-like malar rash with renal involvement: an angioimmunoblastic T-cell lymphoma - A case report.

作者信息

Dalbeni Andrea, Gomarasca Luca, Bellocchi Maria C, Nuvolari Roberta, Bertagnin Matteo, Imbalzano Egidio, Fondrieschi Luigi, Minuz Pietro

机构信息

Section of Medicine, Department of Medicine, University of Verona Verona, Italy.

Department of Internal Medicine and Medical Therapy, University of Messina Messina, Italy.

出版信息

Clin Case Rep. 2015 Jan;3(1):46-9. doi: 10.1002/ccr3.145. Epub 2014 Oct 15.

DOI:10.1002/ccr3.145
PMID:25678974
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4317212/
Abstract

Cutaneous malar rash and kidney involvement has not previously been reported as presenting symptoms of an angioimmunoblastic T-cell lymphoma (AITL). We report a case of a woman with erythematous rash. A PET-CT revealed a lymphadenopathy and splenomegaly. An inguinal lymph node biopsy showed an AITL. There was clinical improvement after prednisone.

摘要

此前尚无报道称皮肤颧部皮疹和肾脏受累是血管免疫母细胞性T细胞淋巴瘤(AITL)的首发症状。我们报告一例患有红斑疹的女性病例。正电子发射断层扫描-计算机断层扫描(PET-CT)显示有淋巴结病和脾肿大。腹股沟淋巴结活检显示为AITL。使用泼尼松后临床症状有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ce/4317212/6d1aab0fd112/ccr30003-0046-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ce/4317212/2640275b6118/ccr30003-0046-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ce/4317212/6d1aab0fd112/ccr30003-0046-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ce/4317212/2640275b6118/ccr30003-0046-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7ce/4317212/6d1aab0fd112/ccr30003-0046-f2.jpg

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本文引用的文献

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Angioimmunoblastic T-cell lymphoma with cutaneous involvement: a case report with subtle histologic changes and clonal T-cell proliferation.伴有皮肤受累的血管免疫母细胞性T细胞淋巴瘤:1例具有细微组织学改变和克隆性T细胞增殖的病例报告
Arch Pathol Lab Med. 2004 Oct;128(10):e122-4. doi: 10.5858/2004-128-e122-ATLWCI.
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A male with angioimmunoblastic T-cell lymphoma and proliferative glomerulonephritis.一名患有血管免疫母细胞性T细胞淋巴瘤和增殖性肾小球肾炎的男性。
Ann Hematol. 2004 Jul;83(7):455-9. doi: 10.1007/s00277-003-0828-5. Epub 2004 Mar 18.
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Cutaneous relapse of angioimmunoblastic lymphadenopathy-type peripheral T-cell lymphoma mimicking an exanthematous drug eruption.
血管免疫母细胞性淋巴结病样外周T细胞淋巴瘤的皮肤复发,酷似药疹样皮疹。
Int J Dermatol. 2003 Oct;42(10):816-8. doi: 10.1046/j.1365-4362.2003.01721.x.
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Cutaneous manifestations of angioimmunoblastic lymphadenopathy.血管免疫母细胞性淋巴结病的皮肤表现
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