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[可可毛色二孢菌所致角膜炎:1例报告及文献复习]

[Keratitis by Lasiodiplodia theobromae: a case report and literature review].

作者信息

Samudio Margarita, Laspina Florentina, Fariña Norma, Franco Alicia, Mino de Kaspar Herminia, Giusiano Gustavo

出版信息

Rev Chilena Infectol. 2014 Dec;31(6):750-4. doi: 10.4067/S0716-10182014000600018.

Abstract

We report a case of mycotic keratitis caused by Lasiodiplodia theobromae in a 60-year-old man with a history of ocular trauma with vegetable matter. Ophthalmological assessment with slit-lamp and microbiological evaluation of the corneal ulcer by conventional microbiological techniques were performed. Mycology study of the corneal scraping showed the presence of fungal filaments and the isolate was identified as Lasiodiplodia theobromae. Patient was treated with natamycin 5% and fluconazole 0.2% for 37 days. The infection was controlled but the corneal scars required a cornea transplant. This is the first case of keratitis by Lasiodiplodia theobromae in Paraguay. Difficulties in the management of these cases, which often requires surgical procedures, are discussed.

摘要

我们报告一例由可可毛色二孢菌引起的真菌性角膜炎病例,患者为一名60岁男性,有眼部被植物性物质创伤史。通过裂隙灯进行眼科评估,并采用传统微生物学技术对角膜溃疡进行微生物学评估。角膜刮片的真菌学研究显示存在真菌丝,分离菌株被鉴定为可可毛色二孢菌。患者接受了5%那他霉素和0.2%氟康唑治疗37天。感染得到控制,但角膜瘢痕需要进行角膜移植。这是巴拉圭首例由可可毛色二孢菌引起的角膜炎病例。文中讨论了这些病例管理中的困难,这类病例往往需要手术治疗。

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