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拉氏拟青霉致异基因造血干细胞移植受者侵袭性鼻窦真菌病 1 例报告并文献复习

Invasive Rhinosinusitis Caused by Lasiodiplodia theobromae in an Allogeneic Hematopoietic Cell Transplant Recipient Case Report and Review of Literature.

机构信息

Infectious Disease Department, Jackson Memorial Hospital, Miami, FL, USA.

Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, 1120 NW 14th St Suite 851, Miami, FL, 33136, USA.

出版信息

Mycopathologia. 2018 Oct;183(5):841-845. doi: 10.1007/s11046-018-0262-9. Epub 2018 Jun 22.

Abstract

Lasiodiplodia theobromae is a known plant pathogen in tropical and subtropical areas. Few cases have been reported in humans (usually keratitis and endophthalmitis) with only two cases of fungal sinusitis in immunocompromised and immunocompetent patients published to date. We report a case of invasive sinusitis secondary to L. theobromae in an allogeneic hematopoietic cell transplant recipient successfully treated with surgical debridement and triazole antifungals with a review of available literature.

摘要

热带和亚热带地区已知的植物病原体是胶孢炭疽菌。在人类中报告的病例很少(通常是角膜炎和眼内炎),迄今为止仅发表了两例免疫抑制和免疫功能正常的患者的真菌性鼻窦炎病例。我们报告了一例异基因造血细胞移植受者继发于胶孢炭疽菌的侵袭性鼻窦炎,通过手术清创和三唑类抗真菌药物成功治疗,并对现有文献进行了回顾。

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