van Dooren-Greebe R J, van de Kerkhof P C, Chang A, Happle R
Department of Dermatology, University of Nijmegen, The Netherlands.
Acta Derm Venereol. 1989;69(4):344-6.
In a patient affected with acrodermatitis continua Hallopeau, acitretin (Ro 10-1670) monotherapy resulted in a complete clearance of pustulation at a dosage of 45 mg per day. At this dosage the leukotriene B4-induced intraepidermal accumulation of polymorphonuclear leukocytes was markedly inhibited.
在一名患有连续性肢端皮炎(Hallopeau型)的患者中,阿维A(Ro 10 - 1670)单药治疗以每日45毫克的剂量使脓疱完全消退。在此剂量下,白三烯B4诱导的多形核白细胞在表皮内的积聚受到明显抑制。