Quandt Dagmar, Seliger Barbara
Institute of Medical Immunology, Martin-Luther University Halle-Wittenberg, Magdeburger Str. 2, 06112, Halle, Germany.
Cancer Immunol Immunother. 2015 Apr;64(4):519-26. doi: 10.1007/s00262-015-1661-0. Epub 2015 Feb 14.
It has become evident that combinatorial treatments with "old fashioned" chemo- and radiotherapy together with DC vaccines, T cell-based approaches therapy by small molecules or novel immunotherapeutic strategies with antibodies are the most promising approaches, but the combinations and sequence of administration has still to be investigated and appear to be tumor specific.
显而易见,将“传统的”化疗和放疗与树突状细胞疫苗、基于小分子的T细胞疗法或抗体新型免疫治疗策略相结合的联合治疗是最具前景的方法,但给药的组合和顺序仍有待研究,且似乎具有肿瘤特异性。