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使用一种皮质类固醇单次给药,敷于水胶体封闭敷料下一周,用于治疗银屑病和其他皮肤病。

Treatment of psoriasis and other dermatoses with a single application of a corticosteroid left under a hydrocolloid occlusive dressing for one week.

作者信息

Juhlin L

机构信息

Department of Dermatology, University Hospital, Uppsala, Sweden.

出版信息

Acta Derm Venereol. 1989;69(4):355-7.

PMID:2568063
Abstract

Lotions of five different corticosteroids were applied on 3 X 4 cm areas of large infiltrated chronic psoriatic plaque in eight patients, and left occluded with a hydrocolloid dressing (Actiderm) for one week. Area treated with clobetasol, betamethasone and triamcinolone were clinically healed within one week in four patients, but slight residual erythema was observed in the other four. Hydrocortisone-treated areas showed better improvement than the non-steroid-treated control area, where infiltration and erythema remained unchanged. In 44 patients with psoriasis, lichen planus, chronic lichenified eczema, discoid lupus erythematosus and necrobiosis lipoidica, treatment with betamethasone applied 1-3 times under Actiderm once a week healed the lesions. The skin-coloured Actiderm is easy to apply and wear and does not loosen when taking a shower or hot bath.

摘要

在8名患者的3×4平方厘米大面积浸润性慢性银屑病斑块区域涂抹5种不同的皮质类固醇洗剂,并用亲水性敷料(Actiderm)封闭一周。使用氯倍他索、倍他米松和曲安奈德治疗的区域,4名患者在一周内临床治愈,但另外4名患者仍观察到轻微的残余红斑。氢化可的松治疗区域比未用类固醇治疗的对照区域改善更明显,对照区域的浸润和红斑没有变化。在44例患有银屑病、扁平苔藓、慢性苔藓化湿疹、盘状红斑狼疮和类脂质渐进性坏死的患者中,每周使用Actiderm封闭1 - 3次倍他米松进行治疗,可使皮损愈合。肤色的Actiderm易于涂抹和穿戴,洗澡或洗热水澡时不会脱落。

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