Barrera-Cruz Antonio, Díaz-Ramos Rita Delia, Viniegra-Osorio Arturo, Grajales-Muñiz Concepción, Dávila-Torres Javier
Coordinación de Programas Médicos, Coordinación Técnica de Excelencia Clínica, Instituto Mexicano del Seguro Social, Distrito Federal, México.
Rev Med Inst Mex Seguro Soc. 2015 Jan-Feb;53(1):102-19.
Chikungunya fever is an emerging disease caused by an alphavirus belonging to the Togaviridae family, transmitted by the bite of Aedes genus species: Aedesaegypti and Aedesalbopictus. In 2013, PAHO/WHO received confirmation of the first cases of indigenous transmission of chikungunya in the Americas. This disease may be acute, subacute and chronic, affecting all age groups. Following an incubation period from three to seven days, the patient usually begins with a high fever (greater than 39 °C), arthralgia, back pain, headache, nausea, vomiting, arthritis, rash, and conjunctivitis (acute phase: 3-10 days). Most patients recover fully, but in some cases, joint involvement may persist chronically and cause discapacity and affect life quality. Serious complications are rare, however, attention must be focused on vulnerable populations (the elderly, children and pregnant women). So far, there is no specific antiviral treatment or effective vaccine, so it is giving priority symptomatic and supportive treatment for the acute phase and make an early diagnosis of atypical and severe forms, and to implement effective prevention and control measures. Given the eco-epidemiological conditions and distribution of vectors in the region of the Americas, the spread of the virus to other countries is likely, so that health professionals should be aware of and identify risk factors and major clinical manifestations, allow timely prevention and safe and effective treatment of this disease.
基孔肯雅热是一种由属于披膜病毒科的甲病毒引起的新发疾病,通过伊蚊属物种:埃及伊蚊和白纹伊蚊叮咬传播。2013年,泛美卫生组织/世界卫生组织收到了美洲首例基孔肯雅热本土传播病例的确认报告。这种疾病可能是急性、亚急性和慢性的,影响所有年龄组。在3至7天的潜伏期后,患者通常开始出现高热(高于39°C)、关节痛、背痛、头痛、恶心、呕吐、关节炎、皮疹和结膜炎(急性期:3 - 10天)。大多数患者可完全康复,但在某些情况下,关节受累可能会长期持续并导致残疾,影响生活质量。严重并发症很少见,然而,必须关注弱势群体(老年人、儿童和孕妇)。到目前为止,尚无特异性抗病毒治疗方法或有效的疫苗,因此急性期优先给予对症和支持治疗,并对非典型和严重形式进行早期诊断,以及实施有效的预防和控制措施。鉴于美洲地区的生态流行病学状况和病媒分布,该病毒有可能传播到其他国家,因此卫生专业人员应了解并识别危险因素和主要临床表现,以便及时预防和安全有效地治疗这种疾病。