一名91岁间变性甲状腺癌女性对每周一次的卡铂-多西他赛化疗的完全缓解。

Complete response to weekly carboplatin-docetaxel chemotherapy in a 91-year-old woman with anaplastic thyroid cancer.

作者信息

Koussis Haralabos, Giorgi Carlo Alberto, Di Liso Elisabetta, Carlucci Maria Concetta, Fassina Ambrogio, Marioni Gino, Conte Pier Franco

机构信息

Division of Oncology 2, Istituto Oncologico Veneto (IOV-IRCCS), Padova, Italy.

出版信息

Am J Otolaryngol. 2015 Mar-Apr;36(2):268-72. doi: 10.1016/j.amjoto.2014.03.006. Epub 2014 Mar 27.

DOI:10.1016/j.amjoto.2014.03.006

PMID:25681954

Abstract

Anaplastic thyroid cancer (ATC) is an unusual tumor with the worst prognosis among thyroid malignancies. Treatment of the patients diagnosed with ATC is not standardized and the feasible options include surgery, radiotherapy and chemotherapy. ATC cannot be regarded as a very chemo-sensitive tumor. Herein, we reported a case of a 91-year-old woman with complete response after induction chemotherapy (weekly carboplatin and docetaxel) that underwent subsequent radiotherapy.

摘要

间变性甲状腺癌（ATC）是一种罕见的肿瘤，在甲状腺恶性肿瘤中预后最差。被诊断为ATC的患者的治疗并不规范，可行的治疗选择包括手术、放疗和化疗。ATC不能被视为对化疗非常敏感的肿瘤。在此，我们报告了一例91岁女性患者，在接受诱导化疗（每周使用卡铂和多西他赛）后出现完全缓解，随后接受了放疗。