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经腹分娩后发热、子宫内膜炎及伤口感染的危险因素。

Risk factors for fever, endometritis and wound infection after abdominal delivery.

作者信息

Suonio S, Saarikoski S, Vohlonen I, Kauhanen O

机构信息

Department of Obstetrics and Gynaecology, University Central Hospital, Kuopio, Finland.

出版信息

Int J Gynaecol Obstet. 1989 Jun;29(2):135-42. doi: 10.1016/0020-7292(89)90843-6.

Abstract

Risk factors for postoperative fever, endometritis and wound infection were analyzed in 761 consecutive cesarean sections. Postoperative fever was observed in 12%, endometritis in 4.7% and wound infection in 3% of cases. The relative risk for postoperative fever was increased in cases with postoperative hematoma (relative risk = 16.0), in cases with blood loss over 500 g (relative risk = 1.8) and if the duration of labor exceeded 6 h (relative risk = 1.9). The only significant risk factors for endometritis were amnionitis (relative risk = 8.7), postoperative hematoma (relative risk = 5.0) and age under 24 years (relative risk = 3.0). Wound infections were less frequent in cases with previous cesarean sections (relative risk = 0.15) and after elective cesarean sections (relative risk = 0.22), but duration of operation over 1 h (relative risk = 2.8), induction of labor (relative risk = 3.2) and puerperal endometritis (relative risk = 7.9) increased the risk of wound infection. By elimination of amnionitis and postoperative hematomas the rate of endometritis would have diminished only from 4.7% to 3.8%, a percentage equally unacceptable; diagnostics and prevention should be directed to young patients undergoing caesarean section. Besides technical procedures prevention of endometritis is important for the prevention of wound infection. In hospitals with low postcesarean infectious morbidity antibiotic prophylaxis seems to be unwarranted.

摘要

对761例连续剖宫产病例分析了术后发热、子宫内膜炎和伤口感染的危险因素。12%的病例出现术后发热,4.7%出现子宫内膜炎,3%出现伤口感染。术后有血肿的病例术后发热的相对风险增加(相对风险=16.0),失血超过500g的病例(相对风险=1.8)以及产程超过6小时的病例(相对风险=1.9)。子宫内膜炎的唯一显著危险因素是羊膜炎(相对风险=8.7)、术后血肿(相对风险=5.0)和24岁以下年龄(相对风险=3.0)。既往有剖宫产史的病例(相对风险=0.15)和择期剖宫产后伤口感染较少见,但手术时间超过1小时(相对风险=2.8)、引产(相对风险=3.2)和产褥期子宫内膜炎(相对风险=7.9)会增加伤口感染的风险。通过消除羊膜炎和术后血肿,子宫内膜炎的发生率仅从4.7%降至3.8%,这一百分比同样不可接受;诊断和预防应针对接受剖宫产的年轻患者。除技术操作外,预防子宫内膜炎对预防伤口感染也很重要。在剖宫产术后感染发病率较低的医院,抗生素预防似乎没有必要。

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