巴西阿雷格里港学童的哮喘和特应性患病率已趋于平稳。
The prevalence of asthma and atopy in schoolchildren from Porto Alegre, Brazil, has plateaued.
作者信息
Schuh Camila, Fritscher Leandro Genehr, Chapman Kenneth R, Fritscher Carlos Cezar
机构信息
Faculty of Medicine, Pontific Catholic University (PUCRS), Ipiranga Av. 6690, Porto Alegre, RS, Brazil.
Asthma and Airway Centre, University Health Network, University of Toronto, Toronto Western Hospital, 399 Bathurst St., Toronto, ON M5T 2S8, Canada.
出版信息
Respir Med. 2015 Mar;109(3):308-11. doi: 10.1016/j.rmed.2015.01.014. Epub 2015 Jan 31.
OBJECTIVE
A significant increase in the prevalence of asthma and atopy was observed in epidemiological studies conducted in 1980, 1989 and 1998, with schoolchildren of Porto Alegre. The present study aims to determine changes in the prevalence of symptoms of current and lifetime asthma and also to document the prevalence of atopy in schoolchildren from a region of Porto Alegre.
METHODS
This was a cross-sectional study in which schoolchildren from 5th to 8th grade (10-18 years), from four schools located in the same geographic area were interviewed. The questionnaire covered symptoms suggestive of lifetime or current asthma (at some point in life or in the last twelve months, respectively). In addition, skin tests were performed in a subset of 241 schoolchildren.
RESULTS
964 students were interviewed from a total of 1195 registered. The prevalence of lifetime asthma symptoms was found to be 41.7%, symptoms of current asthma 14.9% and atopy 52.7%. Compared to previous studies, the prevalence of lifetime asthma and atopy has stabilized while the prevalence of current asthma fell from 22% to 14.9% (P < 0.001).
CONCLUSIONS
In the last decade the prevalence of atopy and lifetime asthma has plateaued, while the prevalence of current asthma fell.
目的
在1980年、1989年和1998年对阿雷格里港学龄儿童进行的流行病学研究中，观察到哮喘和特应性疾病的患病率显著上升。本研究旨在确定当前和终生哮喘症状患病率的变化，并记录阿雷格里港某一地区学龄儿童的特应性疾病患病率。
方法
这是一项横断面研究，对来自同一地理区域的四所学校5至8年级（10 - 18岁）的学龄儿童进行了访谈。问卷涵盖了提示终生或当前哮喘的症状（分别为在生命中的某个时刻或过去十二个月内）。此外，对241名学龄儿童的一个子集进行了皮肤试验。
结果
在总共登记的1195名学生中，对964名学生进行了访谈。发现终生哮喘症状的患病率为41.7%，当前哮喘症状的患病率为14.9%，特应性疾病的患病率为52.7%。与先前的研究相比，终生哮喘和特应性疾病的患病率已趋于稳定，而当前哮喘的患病率从22%降至14.9%（P < 0.001）。
结论
在过去十年中，特应性疾病和终生哮喘的患病率趋于平稳，而当前哮喘的患病率下降。
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