Division of Pulmonary Medicine, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Division of Pulmonary Medicine, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
J Pediatr. 2015 Apr;166(4):1018-21. doi: 10.1016/j.jpeds.2014.12.070. Epub 2015 Feb 12.
To measure the prevalence of obstructive lung disease (OLD) among patients undergoing preoperative pulmonary assessment for idiopathic scoliosis.
This was a retrospective, descriptive review from clinical data in a tertiary care pediatric hospital in the US. Patients (n = 176) with idiopathic scoliosis with Cobb angles of ≥ 40 degrees who performed acceptable and repeatable preoperative pulmonary function testing were included. The primary outcome measure was the forced expiratory volume in the first second (FEV1)/forced vital capacity (FVC) ratio.
The prevalence of OLD (low FEV1/FVC ratio) was 39% (68/176 patients). In multivariate modeling, radiographic measures were poor predictors of pulmonary function outcomes of FVC (r(2) 0.06), FEV1 (r(2) 0.05), FEV1/FVC ratio (r(2) 0.08), and total lung capacity (r(2) 0.06).
OLD is common in patients with idiopathic scoliosis. We recommend preoperative pulmonary function testing for patients with idiopathic scoliosis under consideration for spinal fusion surgery.
测量特发性脊柱侧凸患者术前肺评估中阻塞性肺疾病（OLD）的患病率。
这是美国一家三级儿科医院临床数据的回顾性描述性研究。纳入了 Cobb 角≥40 度的特发性脊柱侧凸且进行了可接受和可重复的术前肺功能检查的患者（n=176）。主要结局指标为第一秒用力呼气量（FEV1）/用力肺活量（FVC）比值。
OLD（低 FEV1/FVC 比值）的患病率为 39%（68/176 例患者）。多元模型分析显示，影像学指标对 FVC（r² 0.06）、FEV1（r² 0.05）、FEV1/FVC 比值（r² 0.08）和总肺容量（r² 0.06）的肺功能结局预测效果较差。
特发性脊柱侧凸患者中 OLD 很常见。我们建议对考虑脊柱融合手术的特发性脊柱侧凸患者进行术前肺功能检查。
