《加拿大风湿病协会/加拿大脊柱关节炎研究联盟脊柱关节炎管理治疗建议2014年更新。第二部分：具体管理建议》
2014 Update of the Canadian Rheumatology Association/Spondyloarthritis Research Consortium of Canada Treatment Recommendations for the Management of Spondyloarthritis. Part II: Specific Management Recommendations.
作者信息
Rohekar Sherry, Chan Jon, Tse Shirley M L, Haroon Nigil, Chandran Vinod, Bessette Louis, Mosher Dianne, Flanagan Cathy, Keen Kevin J, Adams Karen, Mallinson Michael, Thorne Carter, Rahman Proton, Gladman Dafna D, Inman Robert D
机构信息
From the University of Western Ontario, London; University of Toronto; The Hospital for Sick Children; Toronto Western Research Institute University Health Network; Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Canadian Spondylitis Association, Toronto; University of Toronto, Southlake Regional Health Centre, Newmarket, Ontario, Canada; University of British Columbia, Vancouver; University of North British Columbia, Prince George, British Columbia; Laval University, Quebec City, Quebec; Department of Medicine, University of Calgary, Calgary, Alberta; Memorial University, St. John's, Newfoundland, Canada.S. Rohekar, BSc, MD, FRCPC, MSc (Clin. Epi.), Associate Professor of Medicine, University of Western Ontario; J. Chan, BSc, MD, FRCPC; C. Flanagan, MDCM, Clinical Assistant Professor of Medicine, University of British Columbia; S.M. Tse, MD, FRCPC, Associate Professor of Medicine, University of Toronto, The Hospital for Sick Children; N. Haroon, MD, PhD, DM, Assistant Professor of Medicine, University of Toronto, Toronto Western Research Institute University Health Network; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor of Medicine, University of Toronto, and Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; L. Bessette, MD, MSc, FRCPC, Assistant Professor of Medicine; K. Adams, BSc, MD, FRCPC, Associate Professor of Medicine, Laval University; D. Mosher, MD, FRCPC, Professor of Medicine, Department of Medicine, University of Calgary; K.J. Keen, PhD, PStat, PStat(ASA), Associate Professor of Mathematics and Statistics, University of North British Columbia; M. Mallinson, BA, MA, President, Canadian Spondylitis Association; C. Thorne, MD, FRCPC Assistant Professor of Medicine, University of Toronto, Southlake Regional Health Centre; P. Rahman, MD, FRCPC, Associate Dean, Clinical Research and Profess
出版信息
J Rheumatol. 2015 Apr;42(4):665-81. doi: 10.3899/jrheum.141001. Epub 2015 Feb 15.
OBJECTIVE
The Canadian Rheumatology Association (CRA) and the Spondyloarthritis Research Consortium of Canada (SPARCC) have collaborated to update the recommendations for the management of spondyloarthritis (SpA).
METHODS
A working group was assembled and consisted of the SPARCC executive committee, rheumatologist leaders from SPARCC collaborating sites, Canadian rheumatologists from across the country with an interest in SpA (both academic and community), a rheumatology trainee with an interest in SpA, an epidemiologist/health services researcher, a member of the CRA executive, a member of the CRA therapeutics committee, and a patient representative from the Canadian Spondylitis Association. An extensive review was conducted of literature published from 2007 to 2014 involving the management of SpA. The working group created draft recommendations using multiple rounds of Web-based surveys and an in-person conference.
RESULTS
Recommendations for the management of SpA were created. Part II: Specific Management Recommendations addresses management with nonpharmacologic methods, nonsteroidal anti-inflammatories and analgesics, disease-modifying antirheumatic drugs, antibiotics, tumor necrosis factor inhibitors, other biologic agents, and surgery. Also included are 10 modifications for application to juvenile SpA.
CONCLUSION
These recommendations were developed based on current literature and applied to a Canadian healthcare context. It is hoped that implementation of these recommendations will promote best practices in the treatment of SpA.
目的
加拿大风湿病协会（CRA）与加拿大脊柱关节炎研究联盟（SPARCC）合作更新脊柱关节炎（SpA）管理建议。
方法
组建了一个工作组，成员包括SPARCC执行委员会、SPARCC合作站点的风湿病学领军人物、加拿大各地对SpA感兴趣的风湿病学家（包括学术和社区领域）、一名对SpA感兴趣的风湿病学实习生、一名流行病学家/卫生服务研究员、CRA执行委员会成员、CRA治疗委员会成员以及加拿大脊柱炎协会的一名患者代表。对2007年至2014年发表的涉及SpA管理的文献进行了广泛综述。工作组通过多轮基于网络的调查和一次面对面会议制定了建议草案。
结果
制定了SpA管理建议。第二部分：具体管理建议涉及非药物方法、非甾体抗炎药和镇痛药、改善病情抗风湿药、抗生素、肿瘤坏死因子抑制剂、其他生物制剂以及手术的管理。还包括适用于青少年SpA的10项修改建议。
结论
这些建议是基于当前文献制定的，并应用于加拿大的医疗环境。希望这些建议的实施将促进SpA治疗的最佳实践。
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