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印度 HIV 感染的哺乳期母亲维生素 D 缺乏与产后结核病风险。

Vitamin D deficiency and risk of postpartum tuberculosis among HIV-infected breastfeeding mothers in India.

机构信息

<sup>*</sup>Byramjee-Jeejeebhoy Medical College Clinical Trials Unit, Pune, India, <sup>†</sup>Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

<sup>*</sup>Byramjee-Jeejeebhoy Medical College Clinical Trials Unit, Pune, India.

出版信息

Int J Tuberc Lung Dis. 2015 Mar;19(3):302-4. doi: 10.5588/ijtld.14.0658.

DOI:10.5588/ijtld.14.0658
PMID:25686138
Abstract

Some studies have associated low vitamin D levels with the risk of tuberculosis (TB), but its association in human immunodeficiency virus (HIV) infected mothers in a TB-endemic region has not been well studied. We conducted a nested 1:2 case-control study among HIV-infected mothers in western India to evaluate the association between maternal vitamin D levels and the risk of postpartum TB. Vitamin D insufficiency, moderate deficiency and severe deficiency were observed in a high proportion of HIV-infected mothers, but were not associated with the risk of postpartum TB.

摘要

一些研究将维生素 D 水平低与结核病(TB)风险相关联,但在结核病流行地区的 HIV 感染母亲中,其相关性尚未得到很好的研究。我们在印度西部进行了一项嵌套的 1:2 病例对照研究,以评估母体维生素 D 水平与产后结核病风险之间的关系。在 HIV 感染的母亲中,观察到相当比例的维生素 D 不足、中度缺乏和严重缺乏,但与产后 TB 风险无关。

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